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Identification of Effective Anticancer G-Quadruplex-Targeting Chemotypes through the Exploration of a High Diversity Library of Natural Compounds.
Platella C, Ghirga F, Zizza P, Pompili L, Marzano S, Pagano B, Quaglio D, Vergine V, Cammarone S, Botta B, Biroccio A, Mori M, Montesarchio D. Platella C, et al. Among authors: montesarchio d. Pharmaceutics. 2021 Oct 3;13(10):1611. doi: 10.3390/pharmaceutics13101611. Pharmaceutics. 2021. PMID: 34683905 Free PMC article.
Fluorescence enhancement upon G-quadruplex folding: synthesis, structure, and biophysical characterization of a dansyl/cyclodextrin-tagged thrombin binding aptamer.
De Tito S, Morvan F, Meyer A, Vasseur JJ, Cummaro A, Petraccone L, Pagano B, Novellino E, Randazzo A, Giancola C, Montesarchio D. De Tito S, et al. Among authors: montesarchio d. Bioconjug Chem. 2013 Nov 20;24(11):1917-27. doi: 10.1021/bc400352s. Epub 2013 Oct 25. Bioconjug Chem. 2013. PMID: 24094251
G-quadruplex-based aptamers against protein targets in therapy and diagnostics.
Platella C, Riccardi C, Montesarchio D, Roviello GN, Musumeci D. Platella C, et al. Among authors: montesarchio d. Biochim Biophys Acta Gen Subj. 2017 May;1861(5 Pt B):1429-1447. doi: 10.1016/j.bbagen.2016.11.027. Epub 2016 Nov 16. Biochim Biophys Acta Gen Subj. 2017. PMID: 27865995 Free PMC article. Review.
Tandem application of ligand-based virtual screening and G4-OAS assay to identify novel G-quadruplex-targeting chemotypes.
Musumeci D, Amato J, Zizza P, Platella C, Cosconati S, Cingolani C, Biroccio A, Novellino E, Randazzo A, Giancola C, Pagano B, Montesarchio D. Musumeci D, et al. Among authors: montesarchio d. Biochim Biophys Acta Gen Subj. 2017 May;1861(5 Pt B):1341-1352. doi: 10.1016/j.bbagen.2017.01.024. Epub 2017 Jan 24. Biochim Biophys Acta Gen Subj. 2017. PMID: 28130159
Antitumour activity of resveratrol on human melanoma cells: A possible mechanism related to its interaction with malignant cell telomerase.
Platella C, Guida S, Bonmassar L, Aquino A, Bonmassar E, Ravagnan G, Montesarchio D, Roviello GN, Musumeci D, Fuggetta MP. Platella C, et al. Among authors: montesarchio d. Biochim Biophys Acta Gen Subj. 2017 Nov;1861(11 Pt A):2843-2851. doi: 10.1016/j.bbagen.2017.08.001. Epub 2017 Aug 2. Biochim Biophys Acta Gen Subj. 2017. PMID: 28780124
Tailoring a lead-like compound targeting multiple G-quadruplex structures.
Amato J, Platella C, Iachettini S, Zizza P, Musumeci D, Cosconati S, Pagano A, Novellino E, Biroccio A, Randazzo A, Pagano B, Montesarchio D. Amato J, et al. Among authors: montesarchio d. Eur J Med Chem. 2019 Feb 1;163:295-306. doi: 10.1016/j.ejmech.2018.11.058. Epub 2018 Nov 27. Eur J Med Chem. 2019. PMID: 30529547
121 results