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Tricyclic Triazoles as σ1 Receptor Antagonists for Treating Pain.
Díaz JL, Cuevas F, Oliva AI, Font D, Sarmentero MÁ, Álvarez-Bercedo P, López-Valbuena JM, Pericàs MA, Enrech R, Montero A, Yeste S, Vidal-Torres A, Álvarez I, Pérez P, Cendán CM, Cobos EJ, Vela JM, Almansa C. Díaz JL, et al. Among authors: montero a. J Med Chem. 2021 Apr 22;64(8):5157-5170. doi: 10.1021/acs.jmedchem.1c00244. Epub 2021 Apr 7. J Med Chem. 2021. PMID: 33826322
Pharmacological properties of S1RA, a new sigma-1 receptor antagonist that inhibits neuropathic pain and activity-induced spinal sensitization.
Romero L, Zamanillo D, Nadal X, Sánchez-Arroyos R, Rivera-Arconada I, Dordal A, Montero A, Muro A, Bura A, Segalés C, Laloya M, Hernández E, Portillo-Salido E, Escriche M, Codony X, Encina G, Burgueño J, Merlos M, Baeyens JM, Giraldo J, López-García JA, Maldonado R, Plata-Salamán CR, Vela JM. Romero L, et al. Among authors: montero a. Br J Pharmacol. 2012 Aug;166(8):2289-306. doi: 10.1111/j.1476-5381.2012.01942.x. Br J Pharmacol. 2012. PMID: 22404321 Free PMC article.
EST64454: a Highly Soluble σ1 Receptor Antagonist Clinical Candidate for Pain Management.
Díaz JL, García M, Torrens A, Caamaño AM, Enjo J, Sicre C, Lorente A, Port A, Montero A, Yeste S, Álvarez I, Martín M, Maldonado R, de la Puente B, Vidal-Torres A, Cendán CM, Vela JM, Almansa C. Díaz JL, et al. Among authors: montero a. J Med Chem. 2020 Dec 10;63(23):14979-14988. doi: 10.1021/acs.jmedchem.0c01575. Epub 2020 Nov 25. J Med Chem. 2020. PMID: 33237785
710 results