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Page 1
Blood coagulation, inflammation, and malaria.
Francischetti IM, Seydel KB, Monteiro RQ. Francischetti IM, et al. Among authors: monteiro rq. Microcirculation. 2008 Feb;15(2):81-107. doi: 10.1080/10739680701451516. Microcirculation. 2008. PMID: 18260002 Free PMC article. Review.
Defibrotide interferes with several steps of the coagulation-inflammation cycle and exhibits therapeutic potential to treat severe malaria.
Francischetti IM, Oliveira CJ, Ostera GR, Yager SB, Debierre-Grockiego F, Carregaro V, Jaramillo-Gutierrez G, Hume JC, Jiang L, Moretz SE, Lin CK, Ribeiro JM, Long CA, Vickers BK, Schwarz RT, Seydel KB, Iacobelli M, Ackerman HC, Srinivasan P, Gomes RB, Wang X, Monteiro RQ, Kotsyfakis M, Sá-Nunes A, Waisberg M. Francischetti IM, et al. Among authors: monteiro rq. Arterioscler Thromb Vasc Biol. 2012 Mar;32(3):786-98. doi: 10.1161/ATVBAHA.111.240291. Epub 2011 Nov 23. Arterioscler Thromb Vasc Biol. 2012. PMID: 22116094 Free PMC article.
Plasmodium falciparum-infected erythrocytes induce tissue factor expression in endothelial cells and support the assembly of multimolecular coagulation complexes.
Francischetti IM, Seydel KB, Monteiro RQ, Whitten RO, Erexson CR, Noronha AL, Ostera GR, Kamiza SB, Molyneux ME, Ward JM, Taylor TE. Francischetti IM, et al. Among authors: monteiro rq. J Thromb Haemost. 2007 Jan;5(1):155-65. doi: 10.1111/j.1538-7836.2006.02232.x. Epub 2006 Sep 26. J Thromb Haemost. 2007. PMID: 17002660 Free PMC article.
Lufaxin, a novel factor Xa inhibitor from the salivary gland of the sand fly Lutzomyia longipalpis blocks protease-activated receptor 2 activation and inhibits inflammation and thrombosis in vivo.
Collin N, Assumpção TC, Mizurini DM, Gilmore DC, Dutra-Oliveira A, Kotsyfakis M, Sá-Nunes A, Teixeira C, Ribeiro JM, Monteiro RQ, Valenzuela JG, Francischetti IM. Collin N, et al. Among authors: monteiro rq. Arterioscler Thromb Vasc Biol. 2012 Sep;32(9):2185-98. doi: 10.1161/ATVBAHA.112.253906. Epub 2012 Jul 12. Arterioscler Thromb Vasc Biol. 2012. PMID: 22796577 Free PMC article.
Plasmodium falciparum infection induces expression of a mosquito salivary protein (Agaphelin) that targets neutrophil function and inhibits thrombosis without impairing hemostasis.
Waisberg M, Molina-Cruz A, Mizurini DM, Gera N, Sousa BC, Ma D, Leal AC, Gomes T, Kotsyfakis M, Ribeiro JM, Lukszo J, Reiter K, Porcella SF, Oliveira CJ, Monteiro RQ, Barillas-Mury C, Pierce SK, Francischetti IM. Waisberg M, et al. Among authors: monteiro rq. PLoS Pathog. 2014 Sep 11;10(9):e1004338. doi: 10.1371/journal.ppat.1004338. eCollection 2014 Sep. PLoS Pathog. 2014. PMID: 25211214 Free PMC article.
Alboserpin, a factor Xa inhibitor from the mosquito vector of yellow fever, binds heparin and membrane phospholipids and exhibits antithrombotic activity.
Calvo E, Mizurini DM, Sá-Nunes A, Ribeiro JM, Andersen JF, Mans BJ, Monteiro RQ, Kotsyfakis M, Francischetti IM. Calvo E, et al. Among authors: monteiro rq. J Biol Chem. 2011 Aug 12;286(32):27998-8010. doi: 10.1074/jbc.M111.247924. Epub 2011 Jun 14. J Biol Chem. 2011. PMID: 21673107 Free PMC article.
Salivary Thromboxane A2-Binding Proteins from Triatomine Vectors of Chagas Disease Inhibit Platelet-Mediated Neutrophil Extracellular Traps (NETs) Formation and Arterial Thrombosis.
Mizurini DM, Aslan JS, Gomes T, Ma D, Francischetti IM, Monteiro RQ. Mizurini DM, et al. Among authors: monteiro rq. PLoS Negl Trop Dis. 2015 Jun 25;9(6):e0003869. doi: 10.1371/journal.pntd.0003869. eCollection 2015. PLoS Negl Trop Dis. 2015. PMID: 26110417 Free PMC article.
114 results