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Multispecies-targeting siRNAs for the modulation of JAK1 in the skin.
Mol Ther Nucleic Acids. 2024 Jan 9;35(1):102117. doi: 10.1016/j.omtn.2024.102117. eCollection 2024 Mar 12.
Mol Ther Nucleic Acids. 2024.
PMID: 38304729
Free PMC article.
Rational design of a JAK1-selective siRNA inhibitor for the modulation of autoimmunity in the skin.
Tang Q, Fakih HH, Zain Ui Abideen M, Hildebrand SR, Afshari K, Gross KY, Sousa J, Maebius AS, Bartholdy C, Søgaard PP, Jackerott M, Hariharan V, Summers A, Fan X, Okamura K, Monopoli KR, Cooper DA, Echeverria D, Bramato B, McHugh N, Furgal RC, Dresser K, Winter SJ, Biscans A, Chuprin J, Haddadi NS, Sherman S, Yıldız-Altay Ü, Rashighi M, Richmond JM, Bouix-Peter C, Blanchard C, Clauss A, Alterman JF, Khvorova A, Harris JE.
Tang Q, et al. Among authors: monopoli kr.
Nat Commun. 2023 Nov 4;14(1):7099. doi: 10.1038/s41467-023-42714-4.
Nat Commun. 2023.
PMID: 37925520
Free PMC article.
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Asymmetric trichotomous partitioning overcomes dataset limitations in building machine learning models for predicting siRNA efficacy.
Monopoli KR, Korkin D, Khvorova A.
Monopoli KR, et al.
Mol Ther Nucleic Acids. 2023 Jun 14;33:93-109. doi: 10.1016/j.omtn.2023.06.010. eCollection 2023 Sep 12.
Mol Ther Nucleic Acids. 2023.
PMID: 37456778
Free PMC article.
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Functional features defining the efficacy of cholesterol-conjugated, self-deliverable, chemically modified siRNAs.
Shmushkovich T, Monopoli KR, Homsy D, Leyfer D, Betancur-Boissel M, Khvorova A, Wolfson AD.
Shmushkovich T, et al. Among authors: monopoli kr.
Nucleic Acids Res. 2018 Nov 16;46(20):10905-10916. doi: 10.1093/nar/gky745.
Nucleic Acids Res. 2018.
PMID: 30169779
Free PMC article.
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Type 3 Secretion Translocators Spontaneously Assemble a Hexadecameric Transmembrane Complex.
Romano FB, Tang Y, Rossi KC, Monopoli KR, Ross JL, Heuck AP.
Romano FB, et al. Among authors: monopoli kr.
J Biol Chem. 2016 Mar 18;291(12):6304-15. doi: 10.1074/jbc.M115.681031. Epub 2016 Jan 19.
J Biol Chem. 2016.
PMID: 26786106
Free PMC article.
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