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51 results

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Page 1
Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy.
Salatto CT, Miller RA, Cameron KO, Cokorinos E, Reyes A, Ward J, Calabrese MF, Kurumbail RG, Rajamohan F, Kalgutkar AS, Tess DA, Shavnya A, Genung NE, Edmonds DJ, Jatkar A, Maciejewski BS, Amaro M, Gandhok H, Monetti M, Cialdea K, Bollinger E, Kreeger JM, Coskran TM, Opsahl AC, Boucher GG, Birnbaum MJ, DaSilva-Jardine P, Rolph T. Salatto CT, et al. Among authors: monetti m. J Pharmacol Exp Ther. 2017 May;361(2):303-311. doi: 10.1124/jpet.116.237925. Epub 2017 Mar 13. J Pharmacol Exp Ther. 2017. PMID: 28289077
Activation of Liver AMPK with PF-06409577 Corrects NAFLD and Lowers Cholesterol in Rodent and Primate Preclinical Models.
Esquejo RM, Salatto CT, Delmore J, Albuquerque B, Reyes A, Shi Y, Moccia R, Cokorinos E, Peloquin M, Monetti M, Barricklow J, Bollinger E, Smith BK, Day EA, Nguyen C, Geoghegan KF, Kreeger JM, Opsahl A, Ward J, Kalgutkar AS, Tess D, Butler L, Shirai N, Osborne TF, Steinberg GR, Birnbaum MJ, Cameron KO, Miller RA. Esquejo RM, et al. Among authors: monetti m. EBioMedicine. 2018 May;31:122-132. doi: 10.1016/j.ebiom.2018.04.009. Epub 2018 Apr 8. EBioMedicine. 2018. PMID: 29673898 Free PMC article.
Small molecule branched-chain ketoacid dehydrogenase kinase (BDK) inhibitors with opposing effects on BDK protein levels.
Roth Flach RJ, Bollinger E, Reyes AR, Laforest B, Kormos BL, Liu S, Reese MR, Martinez Alsina LA, Buzon L, Zhang Y, Bechle B, Rosado A, Sahasrabudhe PV, Knafels J, Bhattacharya SK, Omoto K, Stansfield JC, Hurley LD, Song L, Luo L, Breitkopf SB, Monetti M, Cunio T, Tierney B, Geoly FJ, Delmore J, Siddall CP, Xue L, Yip KN, Kalgutkar AS, Miller RA, Zhang BB, Filipski KJ. Roth Flach RJ, et al. Among authors: monetti m. Nat Commun. 2023 Aug 9;14(1):4812. doi: 10.1038/s41467-023-40536-y. Nat Commun. 2023. PMID: 37558654 Free PMC article.
Chronic UCN2 treatment desensitizes CRHR2 and improves insulin sensitivity.
Flaherty SE 3rd, Bezy O, Zheng W, Yan D, Li X, Jagarlapudi S, Albuquerque B, Esquejo RM, Peloquin M, Semache M, Mancini A, Kang L, Drujan D, Breitkopf SB, Griffin JD, Jean Beltran PM, Xue L, Stansfield J, Pashos E, Shakey Q, Pehmøller C, Monetti M, Birnbaum MJ, Fortin JP, Wu Z. Flaherty SE 3rd, et al. Among authors: monetti m. Nat Commun. 2023 Jul 4;14(1):3953. doi: 10.1038/s41467-023-39597-w. Nat Commun. 2023. PMID: 37402735 Free PMC article.
Proteomic Profiling of Intra-Islet Features Reveals Substructure-Specific Protein Signatures.
Swensen AC, Veličković D, Williams SM, Moore RJ, Day LZ, Niessen S, Hennessy S, Posso C, Monetti M, Qian WJ, Jacobs J, Whiteley L, Zhu Y, Piehowski PD. Swensen AC, et al. Among authors: monetti m. Mol Cell Proteomics. 2022 Dec;21(12):100426. doi: 10.1016/j.mcpro.2022.100426. Epub 2022 Oct 14. Mol Cell Proteomics. 2022. PMID: 36244662 Free PMC article.
DUX4 expression activates JNK and p38 MAP kinases in myoblasts.
Brennan CM, Hill AS, St Andre M, Li X, Madeti V, Breitkopf S, Garren S, Xue L, Gilbert T, Hadjipanayis A, Monetti M, Emerson CP, Moccia R, Owens J, Christoforou N. Brennan CM, et al. Among authors: monetti m. Dis Model Mech. 2022 Nov 1;15(11):dmm049516. doi: 10.1242/dmm.049516. Epub 2022 Oct 31. Dis Model Mech. 2022. PMID: 36196640 Free PMC article.
GPATCH8 modulates mutant SF3B1 mis-splicing and pathogenicity in hematologic malignancies.
Benbarche S, Pineda JMB, Galvis LB, Biswas J, Liu B, Wang E, Zhang Q, Hogg SJ, Lyttle K, Dahi A, Lewis AM, Sarchi M, Rahman J, Fox N, Ai Y, Mehta S, Garippa R, Ortiz-Pacheco J, Li Z, Monetti M, Stanley RF, Doulatov S, Bradley RK, Abdel-Wahab O. Benbarche S, et al. Among authors: monetti m. Mol Cell. 2024 Apr 21:S1097-2765(24)00284-3. doi: 10.1016/j.molcel.2024.04.006. Online ahead of print. Mol Cell. 2024. PMID: 38688280
Systematic evaluation of AML-associated antigens identifies anti-U5 SNRNP200 therapeutic antibodies for the treatment of acute myeloid leukemia.
Knorr K, Rahman J, Erickson C, Wang E, Monetti M, Li Z, Ortiz-Pacheco J, Jones A, Lu SX, Stanley RF, Baez M, Fox N, Castro C, Marino AE, Jiang C, Penson A, Hogg SJ, Mi X, Nakajima H, Kunimoto H, Nishimura K, Inoue D, Greenbaum B, Knorr D, Ravetch J, Abdel-Wahab O. Knorr K, et al. Among authors: monetti m. Nat Cancer. 2023 Dec;4(12):1675-1692. doi: 10.1038/s43018-023-00656-2. Epub 2023 Oct 23. Nat Cancer. 2023. PMID: 37872381 Free PMC article.
51 results