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Nicotine inhibits the VTA-to-amygdala dopamine pathway to promote anxiety.
Nguyen C, Mondoloni S, Le Borgne T, Centeno I, Come M, Jehl J, Solié C, Reynolds LM, Durand-de Cuttoli R, Tolu S, Valverde S, Didienne S, Hannesse B, Fiancette JF, Pons S, Maskos U, Deroche-Gamonet V, Dalkara D, Hardelin JP, Mourot A, Marti F, Faure P. Nguyen C, et al. Among authors: mondoloni s. Neuron. 2021 Aug 18;109(16):2604-2615.e9. doi: 10.1016/j.neuron.2021.06.013. Epub 2021 Jul 8. Neuron. 2021. PMID: 34242565 Free article.
A Human Polymorphism in CHRNA5 Is Linked to Relapse to Nicotine Seeking in Transgenic Rats.
Forget B, Scholze P, Langa F, Morel C, Pons S, Mondoloni S, Besson M, Durand-de Cuttoli R, Hay A, Tricoire L, Lambolez B, Mourot A, Faure P, Maskos U. Forget B, et al. Among authors: mondoloni s. Curr Biol. 2018 Oct 22;28(20):3244-3253.e7. doi: 10.1016/j.cub.2018.08.044. Epub 2018 Oct 4. Curr Biol. 2018. PMID: 30293722 Free article.
Cell-Specific Neuropharmacology.
Mondoloni S, Durand-de Cuttoli R, Mourot A. Mondoloni S, et al. Trends Pharmacol Sci. 2019 Sep;40(9):696-710. doi: 10.1016/j.tips.2019.07.007. Epub 2019 Aug 7. Trends Pharmacol Sci. 2019. PMID: 31400823 Review.
Chronic nicotine increases midbrain dopamine neuron activity and biases individual strategies towards reduced exploration in mice.
Dongelmans M, Durand-de Cuttoli R, Nguyen C, Come M, Duranté EK, Lemoine D, Brito R, Ahmed Yahia T, Mondoloni S, Didienne S, Bousseyrol E, Hannesse B, Reynolds LM, Torquet N, Dalkara D, Marti F, Mourot A, Naudé J, Faure P. Dongelmans M, et al. Among authors: mondoloni s. Nat Commun. 2021 Nov 26;12(1):6945. doi: 10.1038/s41467-021-27268-7. Nat Commun. 2021. PMID: 34836948 Free PMC article.
17 results