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Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS.
Kim HJ, Kim NC, Wang YD, Scarborough EA, Moore J, Diaz Z, MacLea KS, Freibaum B, Li S, Molliex A, Kanagaraj AP, Carter R, Boylan KB, Wojtas AM, Rademakers R, Pinkus JL, Greenberg SA, Trojanowski JQ, Traynor BJ, Smith BN, Topp S, Gkazi AS, Miller J, Shaw CE, Kottlors M, Kirschner J, Pestronk A, Li YR, Ford AF, Gitler AD, Benatar M, King OD, Kimonis VE, Ross ED, Weihl CC, Shorter J, Taylor JP. Kim HJ, et al. Among authors: molliex a. Nature. 2013 Mar 28;495(7442):467-73. doi: 10.1038/nature11922. Epub 2013 Mar 3. Nature. 2013. PMID: 23455423 Free PMC article.
C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles.
Lee KH, Zhang P, Kim HJ, Mitrea DM, Sarkar M, Freibaum BD, Cika J, Coughlin M, Messing J, Molliex A, Maxwell BA, Kim NC, Temirov J, Moore J, Kolaitis RM, Shaw TI, Bai B, Peng J, Kriwacki RW, Taylor JP. Lee KH, et al. Among authors: molliex a. Cell. 2016 Oct 20;167(3):774-788.e17. doi: 10.1016/j.cell.2016.10.002. Cell. 2016. PMID: 27768896 Free PMC article.
VCP is essential for mitochondrial quality control by PINK1/Parkin and this function is impaired by VCP mutations.
Kim NC, Tresse E, Kolaitis RM, Molliex A, Thomas RE, Alami NH, Wang B, Joshi A, Smith RB, Ritson GP, Winborn BJ, Moore J, Lee JY, Yao TP, Pallanck L, Kundu M, Taylor JP. Kim NC, et al. Among authors: molliex a. Neuron. 2013 Apr 10;78(1):65-80. doi: 10.1016/j.neuron.2013.02.029. Epub 2013 Mar 14. Neuron. 2013. PMID: 23498974 Free PMC article.
Tau protein liquid-liquid phase separation can initiate tau aggregation.
Wegmann S, Eftekharzadeh B, Tepper K, Zoltowska KM, Bennett RE, Dujardin S, Laskowski PR, MacKenzie D, Kamath T, Commins C, Vanderburg C, Roe AD, Fan Z, Molliex AM, Hernandez-Vega A, Muller D, Hyman AA, Mandelkow E, Taylor JP, Hyman BT. Wegmann S, et al. Among authors: molliex am. EMBO J. 2018 Apr 3;37(7):e98049. doi: 10.15252/embj.201798049. Epub 2018 Feb 22. EMBO J. 2018. PMID: 29472250 Free PMC article.
Mitotic memories of gene activity.
Gonzalez I, Molliex A, Navarro P. Gonzalez I, et al. Among authors: molliex a. Curr Opin Cell Biol. 2021 Apr;69:41-47. doi: 10.1016/j.ceb.2020.12.009. Epub 2021 Jan 14. Curr Opin Cell Biol. 2021. PMID: 33454629 Review.
Mitotic bookmarking redundancy by nuclear receptors in pluripotent cells.
Chervova A, Molliex A, Baymaz HI, Coux RX, Papadopoulou T, Mueller F, Hercul E, Fournier D, Dubois A, Gaiani N, Beli P, Festuccia N, Navarro P. Chervova A, et al. Among authors: molliex a. Nat Struct Mol Biol. 2024 Mar;31(3):513-522. doi: 10.1038/s41594-023-01195-1. Epub 2024 Jan 9. Nat Struct Mol Biol. 2024. PMID: 38196033 Free PMC article.