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NisT, the transporter of the lantibiotic nisin, can transport fully modified, dehydrated, and unmodified prenisin and fusions of the leader peptide with non-lantibiotic peptides.
Kuipers A, de Boef E, Rink R, Fekken S, Kluskens LD, Driessen AJ, Leenhouts K, Kuipers OP, Moll GN. Kuipers A, et al. Among authors: moll gn. J Biol Chem. 2004 May 21;279(21):22176-82. doi: 10.1074/jbc.M312789200. Epub 2004 Mar 24. J Biol Chem. 2004. PMID: 15044440 Free article.
Production of dehydroamino acid-containing peptides by Lactococcus lactis.
Rink R, Wierenga J, Kuipers A, Kluskens LD, Driessen AJ, Kuipers OP, Moll GN. Rink R, et al. Among authors: moll gn. Appl Environ Microbiol. 2007 Mar;73(6):1792-6. doi: 10.1128/AEM.02350-06. Epub 2007 Jan 19. Appl Environ Microbiol. 2007. PMID: 17261515 Free PMC article.
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