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Noncanonical protein kinase A activation by oligomerization of regulatory subunits as revealed by inherited Carney complex mutations.
Proc Natl Acad Sci U S A. 2021 May 25;118(21):e2024716118. doi: 10.1073/pnas.2024716118.
Proc Natl Acad Sci U S A. 2021.
PMID: 34006641
Free PMC article.
Measurement of State-Specific Association Constants in Allosteric Sensors through Molecular Stapling and NMR.
Moleschi KJ, Akimoto M, Melacini G.
Moleschi KJ, et al.
J Am Chem Soc. 2015 Aug 26;137(33):10777-85. doi: 10.1021/jacs.5b06557. Epub 2015 Aug 17.
J Am Chem Soc. 2015.
PMID: 26247242
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Allosteric linkers in cAMP signalling.
Akimoto M, Moleschi K, Boulton S, VanSchouwen B, Selvaratnam R, Taylor SS, Melacini G.
Akimoto M, et al. Among authors: moleschi k.
Biochem Soc Trans. 2014 Feb;42(1):139-44. doi: 10.1042/BST20130257.
Biochem Soc Trans. 2014.
PMID: 24450641
Free PMC article.
Review.
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Tapping the translation potential of cAMP signalling: molecular basis for selectivity in cAMP agonism and antagonism as revealed by NMR.
Boulton S, Akimoto M, VanSchouwen B, Moleschi K, Selvaratnam R, Giri R, Melacini G.
Boulton S, et al. Among authors: moleschi k.
Biochem Soc Trans. 2014 Apr;42(2):302-7. doi: 10.1042/BST20130282.
Biochem Soc Trans. 2014.
PMID: 24646235
Review.
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Signaling at crossroads: the dialogue between PDEs and PKA is spoken in multiple languages.
Moleschi K, Melacini G.
Moleschi K, et al.
Biophys J. 2014 Sep 16;107(6):1259-60. doi: 10.1016/j.bpj.2014.07.051.
Biophys J. 2014.
PMID: 25229132
Free PMC article.
No abstract available.
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Mapping the Free Energy Landscape of PKA Inhibition and Activation: A Double-Conformational Selection Model for the Tandem cAMP-Binding Domains of PKA RIα.
Akimoto M, McNicholl ET, Ramkissoon A, Moleschi K, Taylor SS, Melacini G.
Akimoto M, et al. Among authors: moleschi k.
PLoS Biol. 2015 Nov 30;13(11):e1002305. doi: 10.1371/journal.pbio.1002305. eCollection 2015.
PLoS Biol. 2015.
PMID: 26618408
Free PMC article.
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An NMR based phosphodiesterase assay.
Akimoto M , Yu T , Moleschi K , Van K , Anand GS , Melacini G .
Akimoto M , et al. Among authors: moleschi k.
Chem Commun (Camb). 2020 Jul 25;56(58):8091-8094. doi: 10.1039/d0cc01673j. Epub 2020 Jun 17.
Chem Commun (Camb). 2020.
PMID: 32555789
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C-terminus of the P4-ATPase ATP8A2 functions in protein folding and regulation of phospholipid flippase activity.
Chalat M, Moleschi K, Molday RS.
Chalat M, et al. Among authors: moleschi k.
Mol Biol Cell. 2017 Feb 1;28(3):452-462. doi: 10.1091/mbc.E16-06-0453. Epub 2016 Dec 8.
Mol Biol Cell. 2017.
PMID: 27932490
Free PMC article.
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