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Bladder cancer therapy using a conformationally fluid tumoricidal peptide complex.
Brisuda A, Ho JCS, Kandiyal PS, Ng JT, Ambite I, Butler DSC, Háček J, Wan MLY, Tran TH, Nadeem A, Tran TH, Hastings A, Storm P, Fortunati DL, Esmaeili P, Novotna H, Horňák J, Mu YG, Mok KH, Babjuk M, Svanborg C. Brisuda A, et al. Among authors: mok kh. Nat Commun. 2021 Jun 8;12(1):3427. doi: 10.1038/s41467-021-23748-y. Nat Commun. 2021. PMID: 34103518 Free PMC article. Clinical Trial.
HAMLET, protein folding, and tumor cell death.
Mok KH, Pettersson J, Orrenius S, Svanborg C. Mok KH, et al. Biochem Biophys Res Commun. 2007 Mar 2;354(1):1-7. doi: 10.1016/j.bbrc.2006.12.167. Epub 2006 Dec 29. Biochem Biophys Res Commun. 2007. PMID: 17223074 Review. No abstract available.
Can misfolded proteins be beneficial? The HAMLET case.
Pettersson-Kastberg J, Aits S, Gustafsson L, Mossberg A, Storm P, Trulsson M, Persson F, Mok KH, Svanborg C. Pettersson-Kastberg J, et al. Among authors: mok kh. Ann Med. 2009;41(3):162-76. doi: 10.1080/07853890802502614. Ann Med. 2009. PMID: 18985467 Review.
Alternatively folded proteins with unexpected beneficial functions.
Min S, Meehan J, Sullivan LM, Harte NP, Xie Y, Davey GP, Svanborg C, Brodkorb A, Mok KH. Min S, et al. Among authors: mok kh. Biochem Soc Trans. 2012 Aug;40(4):746-51. doi: 10.1042/BST20120029. Biochem Soc Trans. 2012. PMID: 22817727 Review.
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes.
Masters SL, Dunne A, Subramanian SL, Hull RL, Tannahill GM, Sharp FA, Becker C, Franchi L, Yoshihara E, Chen Z, Mullooly N, Mielke LA, Harris J, Coll RC, Mills KH, Mok KH, Newsholme P, Nuñez G, Yodoi J, Kahn SE, Lavelle EC, O'Neill LA. Masters SL, et al. Among authors: mok kh. Nat Immunol. 2010 Oct;11(10):897-904. doi: 10.1038/ni.1935. Epub 2010 Sep 12. Nat Immunol. 2010. PMID: 20835230 Free PMC article.
72 results