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Hot on the trail of TRP channel structure.
Moiseenkova-Bell VY, Wensel TG. Moiseenkova-Bell VY, et al. J Gen Physiol. 2009 Mar;133(3):239-44. doi: 10.1085/jgp.200810123. J Gen Physiol. 2009. PMID: 19237588 Free PMC article. Review. No abstract available.
In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure-Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity.
Xu Z, Wise MC, Chokkalingam N, Walker S, Tello-Ruiz E, Elliott STC, Perales-Puchalt A, Xiao P, Zhu X, Pumroy RA, Fisher PD, Schultheis K, Schade E, Menis S, Guzman S, Andersen H, Broderick KE, Humeau LM, Muthumani K, Moiseenkova-Bell V, Schief WR, Weiner DB, Kulp DW. Xu Z, et al. Adv Sci (Weinh). 2020 Feb 27;7(8):1902802. doi: 10.1002/advs.201902802. eCollection 2020 Apr. Adv Sci (Weinh). 2020. PMID: 32328416 Free PMC article.
Structure of the full-length TRPV2 channel by cryo-EM.
Huynh KW, Cohen MR, Jiang J, Samanta A, Lodowski DT, Zhou ZH, Moiseenkova-Bell VY. Huynh KW, et al. Nat Commun. 2016 Mar 29;7:11130. doi: 10.1038/ncomms11130. Nat Commun. 2016. PMID: 27021073 Free PMC article.
Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM.
Hughes TET, Lodowski DT, Huynh KW, Yazici A, Del Rosario J, Kapoor A, Basak S, Samanta A, Han X, Chakrapani S, Zhou ZH, Filizola M, Rohacs T, Han S, Moiseenkova-Bell VY. Hughes TET, et al. Nat Struct Mol Biol. 2018 Jan;25(1):53-60. doi: 10.1038/s41594-017-0009-1. Epub 2018 Jan 1. Nat Struct Mol Biol. 2018. PMID: 29323279 Free PMC article.
Cryo-EM structure of 5-HT3A receptor in its resting conformation.
Basak S, Gicheru Y, Samanta A, Molugu SK, Huang W, Fuente M, Hughes T, Taylor DJ, Nieman MT, Moiseenkova-Bell V, Chakrapani S. Basak S, et al. Nat Commun. 2018 Feb 6;9(1):514. doi: 10.1038/s41467-018-02997-4. Nat Commun. 2018. PMID: 29410406 Free PMC article.
Structural insights on TRPV5 gating by endogenous modulators.
Hughes TET, Pumroy RA, Yazici AT, Kasimova MA, Fluck EC, Huynh KW, Samanta A, Molugu SK, Zhou ZH, Carnevale V, Rohacs T, Moiseenkova-Bell VY. Hughes TET, et al. Nat Commun. 2018 Oct 10;9(1):4198. doi: 10.1038/s41467-018-06753-6. Nat Commun. 2018. PMID: 30305626 Free PMC article.
Structure-based characterization of novel TRPV5 inhibitors.
Hughes TE, Del Rosario JS, Kapoor A, Yazici AT, Yudin Y, Fluck EC 3rd, Filizola M, Rohacs T, Moiseenkova-Bell VY. Hughes TE, et al. Elife. 2019 Oct 25;8:e49572. doi: 10.7554/eLife.49572. Elife. 2019. PMID: 31647410 Free PMC article.
Structural Pharmacology of TRP Channels.
Zhao Y, McVeigh BM, Moiseenkova-Bell VY. Zhao Y, et al. J Mol Biol. 2021 Aug 20;433(17):166914. doi: 10.1016/j.jmb.2021.166914. Epub 2021 Mar 5. J Mol Biol. 2021. PMID: 33676926 Free PMC article. Review.
47 results