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A novel series of positive modulators of the AMPA receptor: discovery and structure based hit-to-lead studies.
Jamieson C, Basten S, Campbell RA, Cumming IA, Gillen KJ, Gillespie J, Kazemier B, Kiczun M, Lamont Y, Lyons AJ, Maclean JK, Moir EM, Morrow JA, Papakosta M, Rankovic Z, Smith L. Jamieson C, et al. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5753-6. doi: 10.1016/j.bmcl.2010.07.138. Epub 2010 Aug 13. Bioorg Med Chem Lett. 2010. PMID: 20805031 Free article.
Structure based evolution of a novel series of positive modulators of the AMPA receptor.
Jamieson C, Maclean JK, Brown CI, Campbell RA, Gillen KJ, Gillespie J, Kazemier B, Kiczun M, Lamont Y, Lyons AJ, Moir EM, Morrow JA, Pantling J, Rankovic Z, Smith L. Jamieson C, et al. Bioorg Med Chem Lett. 2011 Jan 15;21(2):805-11. doi: 10.1016/j.bmcl.2010.11.098. Epub 2010 Nov 25. Bioorg Med Chem Lett. 2011. PMID: 21190850 Free article.
Design, synthesis, and structure-activity relationship study of bicyclic piperazine analogs of indole-3-carboxamides as novel cannabinoid CB1 receptor agonists.
Moir EM, Yoshiizumi K, Cairns J, Cowley P, Ferguson M, Jeremiah F, Kiyoi T, Morphy R, Tierney J, Wishart G, York M, Baker J, Cottney JE, Houghton AK, McPhail P, Osprey A, Walker G, Adam JM. Moir EM, et al. Bioorg Med Chem Lett. 2010 Dec 15;20(24):7327-30. doi: 10.1016/j.bmcl.2010.10.061. Epub 2010 Oct 20. Bioorg Med Chem Lett. 2010. PMID: 21074434
A novel series of positive modulators of the AMPA receptor: structure-based lead optimization.
Jamieson C, Campbell RA, Cumming IA, Gillen KJ, Gillespie J, Kazemier B, Kiczun M, Lamont Y, Lyons AJ, Maclean JK, Martin F, Moir EM, Morrow JA, Pantling J, Rankovic Z, Smith L. Jamieson C, et al. Bioorg Med Chem Lett. 2010 Oct 15;20(20):6072-5. doi: 10.1016/j.bmcl.2010.08.063. Epub 2010 Aug 15. Bioorg Med Chem Lett. 2010. PMID: 20817521 Free article.
Hidden GBV: Women and substance use.
Moir E, Gwyther S, Wilkins H, Boland G. Moir E, et al. Front Psychiatry. 2022 Aug 8;13:939105. doi: 10.3389/fpsyt.2022.939105. eCollection 2022. Front Psychiatry. 2022. PMID: 36003973 Free PMC article.
36 results