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Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway.
LaMonte GM, Rocamora F, Marapana DS, Gnädig NF, Ottilie S, Luth MR, Worgall TS, Goldgof GM, Mohunlal R, Santha Kumar TR, Thompson JK, Vigil E, Yang J, Hutson D, Johnson T, Huang J, Williams RM, Zou BY, Cheung AL, Kumar P, Egan TJ, Lee MCS, Siegel D, Cowman AF, Fidock DA, Winzeler EA. LaMonte GM, et al. Among authors: mohunlal r. Nat Commun. 2020 Apr 14;11(1):1780. doi: 10.1038/s41467-020-15440-4. Nat Commun. 2020. PMID: 32286267 Free PMC article.