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Molecular mechanisms of SARS-CoV-2 resistance to nirmatrelvir.
Duan Y, Zhou H, Liu X, Iketani S, Lin M, Zhang X, Bian Q, Wang H, Sun H, Hong SJ, Culbertson B, Mohri H, Luck MI, Zhu Y, Liu X, Lu Y, Yang X, Yang K, Sabo Y, Chavez A, Goff SP, Rao Z, Ho DD, Yang H. Duan Y, et al. Among authors: mohri h. Nature. 2023 Oct;622(7982):376-382. doi: 10.1038/s41586-023-06609-0. Epub 2023 Sep 11. Nature. 2023. PMID: 37696289
Multiple pathways for SARS-CoV-2 resistance to nirmatrelvir.
Iketani S, Mohri H, Culbertson B, Hong SJ, Duan Y, Luck MI, Annavajhala MK, Guo Y, Sheng Z, Uhlemann AC, Goff SP, Sabo Y, Yang H, Chavez A, Ho DD. Iketani S, et al. Among authors: mohri h. Nature. 2023 Jan;613(7944):558-564. doi: 10.1038/s41586-022-05514-2. Epub 2022 Nov 9. Nature. 2023. PMID: 36351451 Free PMC article.
Emergence and expansion of SARS-CoV-2 B.1.526 after identification in New York.
Annavajhala MK, Mohri H, Wang P, Nair M, Zucker JE, Sheng Z, Gomez-Simmonds A, Kelley AL, Tagliavia M, Huang Y, Bedford T, Ho DD, Uhlemann AC. Annavajhala MK, et al. Among authors: mohri h. Nature. 2021 Sep;597(7878):703-708. doi: 10.1038/s41586-021-03908-2. Epub 2021 Aug 24. Nature. 2021. PMID: 34428777 Free PMC article.
Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19.
Liu H, Iketani S, Zask A, Khanizeman N, Bednarova E, Forouhar F, Fowler B, Hong SJ, Mohri H, Nair MS, Huang Y, Tay NES, Lee S, Karan C, Resnick SJ, Quinn C, Li W, Shion H, Xia X, Daniels JD, Bartolo-Cruz M, Farina M, Rajbhandari P, Jurtschenko C, Lauber MA, McDonald T, Stokes ME, Hurst BL, Rovis T, Chavez A, Ho DD, Stockwell BR. Liu H, et al. Among authors: mohri h. Nat Commun. 2022 Apr 7;13(1):1891. doi: 10.1038/s41467-022-29413-2. Nat Commun. 2022. PMID: 35393402 Free PMC article.
Antibody evasion by SARS-CoV-2 Omicron subvariants BA.2.12.1, BA.4 and BA.5.
Wang Q, Guo Y, Iketani S, Nair MS, Li Z, Mohri H, Wang M, Yu J, Bowen AD, Chang JY, Shah JG, Nguyen N, Chen Z, Meyers K, Yin MT, Sobieszczyk ME, Sheng Z, Huang Y, Liu L, Ho DD. Wang Q, et al. Among authors: mohri h. Nature. 2022 Aug;608(7923):603-608. doi: 10.1038/s41586-022-05053-w. Epub 2022 Jul 5. Nature. 2022. PMID: 35790190 Free PMC article.
Ad26.COV2.S boosts antibody and T-cell responses following BNT162b2 vaccination.
Iketani S, Liu L, Nair MS, Chandrashekar A, Mohri H, Wang M, Barouch DH, Huang Y, Ho DD. Iketani S, et al. Among authors: mohri h. Emerg Microbes Infect. 2021 Dec;10(1):2220-2222. doi: 10.1080/22221751.2021.2006581. Emerg Microbes Infect. 2021. PMID: 34779713 Free PMC article. No abstract available.
Rebound of SARS-CoV-2 Infection after Nirmatrelvir-Ritonavir Treatment.
Charness ME, Gupta K, Stack G, Strymish J, Adams E, Lindy DC, Mohri H, Ho DD. Charness ME, et al. Among authors: mohri h. N Engl J Med. 2022 Sep 15;387(11):1045-1047. doi: 10.1056/NEJMc2206449. Epub 2022 Sep 7. N Engl J Med. 2022. PMID: 36069968 Free PMC article. No abstract available.
515 results