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Defects in microvillus crosslinking sensitize to colitis and inflammatory bowel disease.
Mödl B, Awad M, Zwolanek D, Scharf I, Schwertner K, Milovanovic D, Moser D, Schmidt K, Pjevac P, Hausmann B, Krauß D, Mohr T, Svinka J, Kenner L, Casanova E, Timelthaler G, Sibilia M, Krieger S, Eferl R. Mödl B, et al. Among authors: mohr t. EMBO Rep. 2023 Oct 9;24(10):e57084. doi: 10.15252/embr.202357084. Epub 2023 Sep 11. EMBO Rep. 2023. PMID: 37691494 Free PMC article.
Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis.
Grabner B, Schramek D, Mueller KM, Moll HP, Svinka J, Hoffmann T, Bauer E, Blaas L, Hruschka N, Zboray K, Stiedl P, Nivarthi H, Bogner E, Gruber W, Mohr T, Zwick RH, Kenner L, Poli V, Aberger F, Stoiber D, Egger G, Esterbauer H, Zuber J, Moriggl R, Eferl R, Győrffy B, Penninger JM, Popper H, Casanova E. Grabner B, et al. Among authors: mohr t. Nat Commun. 2015 Mar 3;6:6285. doi: 10.1038/ncomms7285. Nat Commun. 2015. PMID: 25734337 Free PMC article.
Myeloid STAT3 promotes formation of colitis-associated colorectal cancer in mice.
Pathria P, Gotthardt D, Prchal-Murphy M, Putz EM, Holcmann M, Schlederer M, Grabner B, Crncec I, Svinka J, Musteanu M, Hoffmann T, Filipits M, Berger W, Poli V, Kenner L, Bilban M, Casanova E, Müller M, Strobl B, Bayer E, Mohr T, Sexl V, Eferl R. Pathria P, et al. Among authors: mohr t. Oncoimmunology. 2015 Jan 22;4(4):e998529. doi: 10.1080/2162402X.2014.998529. eCollection 2015 Apr. Oncoimmunology. 2015. PMID: 26137415 Free PMC article.
Hepatic Deletion of Janus Kinase 2 Counteracts Oxidative Stress in Mice.
Themanns M, Mueller KM, Kessler SM, Golob-Schwarzl N, Mohr T, Kaltenecker D, Bourgeais J, Paier-Pourani J, Friedbichler K, Schneller D, Schlederer M, Zebedin-Brandl E, Terracciano LM, Han X, Kenner L, Wagner KU, Mikulits W, Kozlov AV, Heim MH, Gouilleux F, Haybaeck J, Moriggl R. Themanns M, et al. Among authors: mohr t. Sci Rep. 2016 Oct 7;6:34719. doi: 10.1038/srep34719. Sci Rep. 2016. PMID: 27713471 Free PMC article.
STAT1 is a sex-specific tumor suppressor in colitis-associated colorectal cancer.
Crnčec I, Modak M, Gordziel C, Svinka J, Scharf I, Moritsch S, Pathria P, Schlederer M, Kenner L, Timelthaler G, Müller M, Strobl B, Casanova E, Bayer E, Mohr T, Stöckl J, Friedrich K, Eferl R. Crnčec I, et al. Among authors: mohr t. Mol Oncol. 2018 Apr;12(4):514-528. doi: 10.1002/1878-0261.12178. Epub 2018 Feb 20. Mol Oncol. 2018. PMID: 29419930 Free PMC article.
EGFR is required for FOS-dependent bone tumor development via RSK2/CREB signaling.
Linder M, Glitzner E, Srivatsa S, Bakiri L, Matsuoka K, Shahrouzi P, Dumanic M, Novoszel P, Mohr T, Langer O, Wanek T, Mitterhauser M, Wagner EF, Sibilia M. Linder M, et al. Among authors: mohr t. EMBO Mol Med. 2018 Nov;10(11):e9408. doi: 10.15252/emmm.201809408. EMBO Mol Med. 2018. PMID: 30361264 Free PMC article.
IDO1+ Paneth cells promote immune escape of colorectal cancer.
Pflügler S, Svinka J, Scharf I, Crncec I, Filipits M, Charoentong P, Tschurtschenthaler M, Kenner L, Awad M, Stift J, Schernthanner M, Bischl R, Herndler-Brandstetter D, Glitzner E, Moll HP, Casanova E, Timelthaler G, Sibilia M, Gnant M, Lax S, Thaler J, Müller M, Strobl B, Mohr T, Kaser A, Trajanoski Z, Heller G, Eferl R. Pflügler S, et al. Among authors: mohr t. Commun Biol. 2020 May 22;3(1):252. doi: 10.1038/s42003-020-0989-y. Commun Biol. 2020. PMID: 32444775 Free PMC article.
240 results