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STAT3-dependent analysis reveals PDK4 as independent predictor of recurrence in prostate cancer.
Oberhuber M, Pecoraro M, Rusz M, Oberhuber G, Wieselberg M, Haslinger P, Gurnhofer E, Schlederer M, Limberger T, Lagger S, Pencik J, Kodajova P, Högler S, Stockmaier G, Grund-Gröschke S, Aberger F, Bolis M, Theurillat JP, Wiebringhaus R, Weiss T, Haitel A, Brehme M, Wadsak W, Griss J, Mohr T, Hofer A, Jäger A, Pollheimer J, Egger G, Koellensperger G, Mann M, Hantusch B, Kenner L. Oberhuber M, et al. Among authors: mohr t. Mol Syst Biol. 2020 Apr;16(4):e9247. doi: 10.15252/msb.20199247. Mol Syst Biol. 2020. PMID: 32323921 Free PMC article.
Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis.
Grabner B, Schramek D, Mueller KM, Moll HP, Svinka J, Hoffmann T, Bauer E, Blaas L, Hruschka N, Zboray K, Stiedl P, Nivarthi H, Bogner E, Gruber W, Mohr T, Zwick RH, Kenner L, Poli V, Aberger F, Stoiber D, Egger G, Esterbauer H, Zuber J, Moriggl R, Eferl R, Győrffy B, Penninger JM, Popper H, Casanova E. Grabner B, et al. Among authors: mohr t. Nat Commun. 2015 Mar 3;6:6285. doi: 10.1038/ncomms7285. Nat Commun. 2015. PMID: 25734337 Free PMC article.
Myeloid STAT3 promotes formation of colitis-associated colorectal cancer in mice.
Pathria P, Gotthardt D, Prchal-Murphy M, Putz EM, Holcmann M, Schlederer M, Grabner B, Crncec I, Svinka J, Musteanu M, Hoffmann T, Filipits M, Berger W, Poli V, Kenner L, Bilban M, Casanova E, Müller M, Strobl B, Bayer E, Mohr T, Sexl V, Eferl R. Pathria P, et al. Among authors: mohr t. Oncoimmunology. 2015 Jan 22;4(4):e998529. doi: 10.1080/2162402X.2014.998529. eCollection 2015 Apr. Oncoimmunology. 2015. PMID: 26137415 Free PMC article.
Hepatic Deletion of Janus Kinase 2 Counteracts Oxidative Stress in Mice.
Themanns M, Mueller KM, Kessler SM, Golob-Schwarzl N, Mohr T, Kaltenecker D, Bourgeais J, Paier-Pourani J, Friedbichler K, Schneller D, Schlederer M, Zebedin-Brandl E, Terracciano LM, Han X, Kenner L, Wagner KU, Mikulits W, Kozlov AV, Heim MH, Gouilleux F, Haybaeck J, Moriggl R. Themanns M, et al. Among authors: mohr t. Sci Rep. 2016 Oct 7;6:34719. doi: 10.1038/srep34719. Sci Rep. 2016. PMID: 27713471 Free PMC article.
Sensitivity towards the GRP78 inhibitor KP1339/IT-139 is characterized by apoptosis induction via caspase 8 upon disruption of ER homeostasis.
Schoenhacker-Alte B, Mohr T, Pirker C, Kryeziu K, Kuhn PS, Buck A, Hofmann T, Gerner C, Hermann G, Koellensperger G, Keppler BK, Berger W, Heffeter P. Schoenhacker-Alte B, et al. Among authors: mohr t. Cancer Lett. 2017 Sep 28;404:79-88. doi: 10.1016/j.canlet.2017.07.009. Epub 2017 Jul 14. Cancer Lett. 2017. PMID: 28716523
STAT1 is a sex-specific tumor suppressor in colitis-associated colorectal cancer.
Crnčec I, Modak M, Gordziel C, Svinka J, Scharf I, Moritsch S, Pathria P, Schlederer M, Kenner L, Timelthaler G, Müller M, Strobl B, Casanova E, Bayer E, Mohr T, Stöckl J, Friedrich K, Eferl R. Crnčec I, et al. Among authors: mohr t. Mol Oncol. 2018 Apr;12(4):514-528. doi: 10.1002/1878-0261.12178. Epub 2018 Feb 20. Mol Oncol. 2018. PMID: 29419930 Free PMC article.
The Anticancer Ruthenium Compound BOLD-100 Targets Glycolysis and Generates a Metabolic Vulnerability towards Glucose Deprivation.
Baier D, Schoenhacker-Alte B, Rusz M, Pirker C, Mohr T, Mendrina T, Kirchhofer D, Meier-Menches SM, Hohenwallner K, Schaier M, Rampler E, Koellensperger G, Heffeter P, Keppler B, Berger W. Baier D, et al. Among authors: mohr t. Pharmaceutics. 2022 Jan 20;14(2):238. doi: 10.3390/pharmaceutics14020238. Pharmaceutics. 2022. PMID: 35213972 Free PMC article.
240 results