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Dual Piperidine-Based Histamine H3 and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain.
Szczepańska K, Karcz T, Dichiara M, Mogilski S, Kalinowska-Tłuścik J, Pilarski B, Leniak A, Pietruś W, Podlewska S, Popiołek-Barczyk K, Humphrys LJ, Ruiz-Cantero MC, Reiner-Link D, Leitzbach L, Łażewska D, Pockes S, Górka M, Zmysłowski A, Calmels T, Cobos EJ, Marrazzo A, Stark H, Bojarski AJ, Amata E, Kieć-Kononowicz K. Szczepańska K, et al. Among authors: mogilski s. J Med Chem. 2023 Jul 27;66(14):9658-9683. doi: 10.1021/acs.jmedchem.3c00430. Epub 2023 Jul 7. J Med Chem. 2023. PMID: 37418295 Free PMC article.
Pharmacophore models based studies on the affinity and selectivity toward 5-HT1A with reference to α1-adrenergic receptors among arylpiperazine derivatives of phenytoin.
Handzlik J, Szymańska E, Nędza K, Kubacka M, Siwek A, Mogilski S, Handzlik J, Filipek B, Kieć-Kononowicz K. Handzlik J, et al. Among authors: mogilski s. Bioorg Med Chem. 2011 Feb 1;19(3):1349-60. doi: 10.1016/j.bmc.2010.11.051. Epub 2010 Dec 5. Bioorg Med Chem. 2011. PMID: 21232965
Antidepressant-like activity of aroxyalkyl derivatives of 2-methoxyphenylpiperazine and evidence for the involvement of serotonin receptor subtypes in their mechanism of action.
Kubacka M, Mogilski S, Bednarski M, Nowiński L, Dudek M, Żmudzka E, Siwek A, Waszkielewicz AM, Marona H, Satała G, Bojarski A, Filipek B, Pytka K. Kubacka M, et al. Among authors: mogilski s. Pharmacol Biochem Behav. 2016 Feb;141:28-41. doi: 10.1016/j.pbb.2015.11.013. Epub 2015 Dec 2. Pharmacol Biochem Behav. 2016. PMID: 26647362
Biphenyloxy-alkyl-piperidine and azepane derivatives as histamine H3 receptor ligands.
Łażewska D, Kaleta M, Schwed JS, Karcz T, Mogilski S, Latacz G, Olejarz A, Siwek A, Kubacka M, Lubelska A, Honkisz E, Handzlik J, Filipek B, Stark H, Kieć-Kononowicz K. Łażewska D, et al. Among authors: mogilski s. Bioorg Med Chem. 2017 Oct 15;25(20):5341-5354. doi: 10.1016/j.bmc.2017.07.058. Epub 2017 Jul 29. Bioorg Med Chem. 2017. PMID: 28797771
Synthesis and biological activity of novel tert-butyl and tert-pentylphenoxyalkyl piperazine derivatives as histamine H3R ligands.
Szczepańska K, Karcz T, Mogilski S, Siwek A, Kuder KJ, Latacz G, Kubacka M, Hagenow S, Lubelska A, Olejarz A, Kotańska M, Sadek B, Stark H, Kieć-Kononowicz K. Szczepańska K, et al. Among authors: mogilski s. Eur J Med Chem. 2018 May 25;152:223-234. doi: 10.1016/j.ejmech.2018.04.043. Epub 2018 Apr 25. Eur J Med Chem. 2018. PMID: 29723785
51 results