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Page 1
Oncogenic KRAS confers chemoresistance by upregulating NRF2.
Tao S, Wang S, Moghaddam SJ, Ooi A, Chapman E, Wong PK, Zhang DD. Tao S, et al. Among authors: moghaddam sj. Cancer Res. 2014 Dec 15;74(24):7430-41. doi: 10.1158/0008-5472.CAN-14-1439. Epub 2014 Oct 22. Cancer Res. 2014. PMID: 25339352 Free PMC article.
IL6 Blockade Reprograms the Lung Tumor Microenvironment to Limit the Development and Progression of K-ras-Mutant Lung Cancer.
Caetano MS, Zhang H, Cumpian AM, Gong L, Unver N, Ostrin EJ, Daliri S, Chang SH, Ochoa CE, Hanash S, Behrens C, Wistuba II, Sternberg C, Kadara H, Ferreira CG, Watowich SS, Moghaddam SJ. Caetano MS, et al. Among authors: moghaddam sj. Cancer Res. 2016 Jun 1;76(11):3189-99. doi: 10.1158/0008-5472.CAN-15-2840. Epub 2016 Apr 1. Cancer Res. 2016. PMID: 27197187 Free PMC article.
COPD-Type lung inflammation promotes K-ras mutant lung cancer through epithelial HIF-1α mediated tumor angiogenesis and proliferation.
De la Garza MM, Cumpian AM, Daliri S, Castro-Pando S, Umer M, Gong L, Khosravi N, Caetano MS, Ramos-Castañeda M, Flores AG, Beltran EC, Tran HT, Tuvim MJ, Ostrin EJ, Dickey BF, Evans CM, Moghaddam SJ. De la Garza MM, et al. Among authors: moghaddam sj. Oncotarget. 2018 Aug 31;9(68):32972-32983. doi: 10.18632/oncotarget.26030. eCollection 2018 Aug 31. Oncotarget. 2018. PMID: 30250643 Free PMC article.
Sex specific function of epithelial STAT3 signaling in pathogenesis of K-ras mutant lung cancer.
Caetano MS, Hassane M, Van HT, Bugarin E, Cumpian AM, McDowell CL, Cavazos CG, Zhang H, Deng S, Diao L, Wang J, Evans SE, Behrens C, Wistuba II, Fuqua SAW, Lin H, Stabile LP, Watowich SS, Kadara H, Moghaddam SJ. Caetano MS, et al. Among authors: moghaddam sj. Nat Commun. 2018 Nov 2;9(1):4589. doi: 10.1038/s41467-018-07042-y. Nat Commun. 2018. PMID: 30389925 Free PMC article.
Augmented Lipocalin-2 Is Associated with Chronic Obstructive Pulmonary Disease and Counteracts Lung Adenocarcinoma Development.
Treekitkarnmongkol W, Hassane M, Sinjab A, Chang K, Hara K, Rahal Z, Zhang J, Lu W, Sivakumar S, McDowell TL, Kantrowitz J, Zhou J, Lang W, Xu L, Ochieng JK, Nunomura-Nakamura S, Deng S, Behrens C, Raso MG, Fukuoka J, Reuben A, Ostrin EJ, Parra E, Solis LM, Spira AE, McAllister F, Cascone T, Wistuba II, Moghaddam SJ, Scheet PA, Fujimoto J, Kadara H. Treekitkarnmongkol W, et al. Among authors: moghaddam sj. Am J Respir Crit Care Med. 2021 Jan 1;203(1):90-101. doi: 10.1164/rccm.202004-1079OC. Am J Respir Crit Care Med. 2021. PMID: 32730093 Free PMC article.
Single-Cell Expression Landscape of SARS-CoV-2 Receptor ACE2 and Host Proteases in Normal and Malignant Lung Tissues from Pulmonary Adenocarcinoma Patients.
Han G, Sinjab A, Hara K, Treekitkarnmongkol W, Brennan P, Chang K, Bogatenkova E, Sanchez-Espiridion B, Behrens C, Solis LM, Gao B, Girard L, Zhang J, Sepesi B, Cascone T, Byers LA, Gibbons DL, Chen J, Moghaddam SJ, Ostrin EJ, Scheet P, Fujimoto J, Shay J, Heymach JV, Minna JD, Dubinett S, Wistuba II, Stevenson CS, Spira AE, Wang L, Kadara H. Han G, et al. Among authors: moghaddam sj. Cancers (Basel). 2021 Mar 12;13(6):1250. doi: 10.3390/cancers13061250. Cancers (Basel). 2021. PMID: 33809063 Free PMC article.
Resolving the Spatial and Cellular Architecture of Lung Adenocarcinoma by Multiregion Single-Cell Sequencing.
Sinjab A, Han G, Treekitkarnmongkol W, Hara K, Brennan PM, Dang M, Hao D, Wang R, Dai E, Dejima H, Zhang J, Bogatenkova E, Sanchez-Espiridion B, Chang K, Little DR, Bazzi S, Tran LM, Krysan K, Behrens C, Duose DY, Parra ER, Raso MG, Solis LM, Fukuoka J, Zhang J, Sepesi B, Cascone T, Byers LA, Gibbons DL, Chen J, Moghaddam SJ, Ostrin EJ, Rosen D, Heymach JV, Scheet P, Dubinett SM, Fujimoto J, Wistuba II, Stevenson CS, Spira A, Wang L, Kadara H. Sinjab A, et al. Among authors: moghaddam sj. Cancer Discov. 2021 Oct;11(10):2506-2523. doi: 10.1158/2159-8290.CD-20-1285. Epub 2021 May 10. Cancer Discov. 2021. PMID: 33972311 Free PMC article.
Targeting IL-1β as an immunopreventive and therapeutic modality for K-ras-mutant lung cancer.
Yuan B, Clowers MJ, Velasco WV, Peng S, Peng Q, Shi Y, Ramos-Castaneda M, Zarghooni M, Yang S, Babcock RL, Chang SH, Heymach JV, Zhang J, Ostrin EJ, Watowich SS, Kadara H, Moghaddam SJ. Yuan B, et al. Among authors: moghaddam sj. JCI Insight. 2022 Jun 8;7(11):e157788. doi: 10.1172/jci.insight.157788. JCI Insight. 2022. PMID: 35471938 Free PMC article.
An atlas of epithelial cell states and plasticity in lung adenocarcinoma.
Han G, Sinjab A, Rahal Z, Lynch AM, Treekitkarnmongkol W, Liu Y, Serrano AG, Feng J, Liang K, Khan K, Lu W, Hernandez SD, Liu Y, Cao X, Dai E, Pei G, Hu J, Abaya C, Gomez-Bolanos LI, Peng F, Chen M, Parra ER, Cascone T, Sepesi B, Moghaddam SJ, Scheet P, Negrao MV, Heymach JV, Li M, Dubinett SM, Stevenson CS, Spira AE, Fujimoto J, Solis LM, Wistuba II, Chen J, Wang L, Kadara H. Han G, et al. Among authors: moghaddam sj. Nature. 2024 Mar;627(8004):656-663. doi: 10.1038/s41586-024-07113-9. Epub 2024 Feb 28. Nature. 2024. PMID: 38418883 Free PMC article.
46 results