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Electrogenic reaction step and phospholipid translocation pathway of the mammalian P4-ATPase ATP8A2.
FEBS Lett. 2023 Feb;597(4):495-503. doi: 10.1002/1873-3468.14459. Epub 2022 Aug 9.
FEBS Lett. 2023.
PMID: 35945663
Free article.
P4-ATPases as Phospholipid Flippases-Structure, Function, and Enigmas.
Andersen JP, Vestergaard AL, Mikkelsen SA, Mogensen LS, Chalat M, Molday RS.
Andersen JP, et al. Among authors: mogensen ls.
Front Physiol. 2016 Jul 8;7:275. doi: 10.3389/fphys.2016.00275. eCollection 2016.
Front Physiol. 2016.
PMID: 27458383
Free PMC article.
Review.
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Disease mutations reveal residues critical to the interaction of P4-ATPases with lipid substrates.
Gantzel RH, Mogensen LS, Mikkelsen SA, Vilsen B, Molday RS, Vestergaard AL, Andersen JP.
Gantzel RH, et al. Among authors: mogensen ls.
Sci Rep. 2017 Sep 5;7(1):10418. doi: 10.1038/s41598-017-10741-z.
Sci Rep. 2017.
PMID: 28874751
Free PMC article.
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Asparagine 905 of the mammalian phospholipid flippase ATP8A2 is essential for lipid substrate-induced activation of ATP8A2 dephosphorylation.
Mikkelsen SA, Mogensen LS, Vilsen B, Molday RS, Vestergaard AL, Andersen JP.
Mikkelsen SA, et al. Among authors: mogensen ls.
J Biol Chem. 2019 Apr 12;294(15):5970-5979. doi: 10.1074/jbc.RA118.007240. Epub 2019 Feb 13.
J Biol Chem. 2019.
PMID: 30760526
Free PMC article.
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Phosphatidylserine flipping by the P4-ATPase ATP8A2 is electrogenic.
Tadini-Buoninsegni F, Mikkelsen SA, Mogensen LS, Molday RS, Andersen JP.
Tadini-Buoninsegni F, et al. Among authors: mogensen ls.
Proc Natl Acad Sci U S A. 2019 Aug 13;116(33):16332-16337. doi: 10.1073/pnas.1910211116. Epub 2019 Aug 1.
Proc Natl Acad Sci U S A. 2019.
PMID: 31371510
Free PMC article.
Item in Clipboard
On the track of the lipid transport pathway of the phospholipid flippase ATP8A2 - Mutation analysis of residues of the transmembrane segments M1, M2, M3 and M4.
Mogensen LS, Mikkelsen SA, Tadini-Buoninsegni F, Holm R, Matsell E, Vilsen B, Molday RS, Andersen JP.
Mogensen LS, et al.
Biochim Biophys Acta Mol Cell Res. 2024 Jan;1871(1):119570. doi: 10.1016/j.bbamcr.2023.119570. Epub 2023 Sep 9.
Biochim Biophys Acta Mol Cell Res. 2024.
PMID: 37678495
Free article.
Review.
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