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Pediatric ALL relapses after allo-SCT show high individuality, clonal dynamics, selective pressure, and druggable targets.
Hoell JI, Ginzel S, Kuhlen M, Kloetgen A, Gombert M, Fischer U, Hein D, Demir S, Stanulla M, Schrappe M, Zur Stadt U, Bader P, Babor F, Schuster F, Strahm B, Alten J, Moericke A, Escherich G, von Stackelberg A, Thiele R, McHardy AC, Peters C, Bornhauser B, Bourquin JP, Krause S, Enczmann J, Meyer LH, Eckert C, Borkhardt A, Meisel R. Hoell JI, et al. Among authors: moericke a. Blood Adv. 2019 Oct 22;3(20):3143-3156. doi: 10.1182/bloodadvances.2019000051. Blood Adv. 2019. PMID: 31648313 Free PMC article.
Gene expression shift towards normal B cells, decreased proliferative capacity and distinct surface receptors characterize leukemic blasts persisting during induction therapy in childhood acute lymphoblastic leukemia.
Rhein P, Scheid S, Ratei R, Hagemeier C, Seeger K, Kirschner-Schwabe R, Moericke A, Schrappe M, Spang R, Ludwig WD, Karawajew L. Rhein P, et al. Among authors: moericke a. Leukemia. 2007 May;21(5):897-905. doi: 10.1038/sj.leu.2404613. Epub 2007 Mar 1. Leukemia. 2007. PMID: 17330098
Varicella vaccination in a child with acute lymphoblastic leukaemia.
Schrauder A, Henke-Gendo C, Seidemann K, Sasse M, Cario G, Moericke A, Schrappe M, Heim A, Wessel A. Schrauder A, et al. Among authors: moericke a. Lancet. 2007 Apr 7;369(9568):1232. doi: 10.1016/S0140-6736(07)60567-4. Lancet. 2007. PMID: 17416267 No abstract available.
Pediatric precursor T lymphoblastic leukemia and lymphoblastic lymphoma: Differences in the common regions with loss of heterozygosity at chromosome 6q and their prognostic impact.
Burkhardt B, Moericke A, Klapper W, Greene F, Salzburg J, Damm-Welk C, Zimmermann M, Strauch K, Ludwig WD, Schrappe M, Reiter A. Burkhardt B, et al. Among authors: moericke a. Leuk Lymphoma. 2008 Mar;49(3):451-61. doi: 10.1080/10428190701824551. Leuk Lymphoma. 2008. PMID: 18297521
Frequency and clinical relevance of DNA microsatellite alterations of the CDKN2A/B, ATM and p53 gene loci: a comparison between pediatric precursor T-cell lymphoblastic lymphoma and T-cell lymphoblastic leukemia.
Krieger D, Moericke A, Oschlies I, Zimmermann M, Schrappe M, Reiter A, Burkhardt B. Krieger D, et al. Among authors: moericke a. Haematologica. 2010 Jan;95(1):158-62. doi: 10.3324/haematol.2009.007526. Epub 2009 Jul 7. Haematologica. 2010. PMID: 19586936 Free PMC article.
Presence of the P2RY8-CRLF2 rearrangement is associated with a poor prognosis in non-high-risk precursor B-cell acute lymphoblastic leukemia in children treated according to the ALL-BFM 2000 protocol.
Cario G, Zimmermann M, Romey R, Gesk S, Vater I, Harbott J, Schrauder A, Moericke A, Izraeli S, Akasaka T, Dyer MJ, Siebert R, Schrappe M, Stanulla M. Cario G, et al. Among authors: moericke a. Blood. 2010 Jul 1;115(26):5393-7. doi: 10.1182/blood-2009-11-256131. Epub 2010 Apr 8. Blood. 2010. PMID: 20378752 Free article.
Very early/early relapses of acute lymphoblastic leukemia show unexpected changes of clonal markers and high heterogeneity in response to initial and relapse treatment.
Eckert C, Flohr T, Koehler R, Hagedorn N, Moericke A, Stanulla M, Kirschner-Schwabe R, Cario G, Stackelberg A, Bartram CR, Henze G, Schrappe M, Schrauder A. Eckert C, et al. Among authors: moericke a. Leukemia. 2011 Aug;25(8):1305-13. doi: 10.1038/leu.2011.89. Epub 2011 May 6. Leukemia. 2011. PMID: 21546902
The thirteenth international childhood acute lymphoblastic leukemia workshop report: La Jolla, CA, USA, December 7-9, 2011.
Hunger SP, Baruchel A, Biondi A, Evans WE, Jeha S, Loh M, Moericke A, Pieters R, Relling MV, Schmiegelow K, Schrappe M, Silverman LB, Stanulla M, Valsecchi MG, Vora A, Pui CH. Hunger SP, et al. Among authors: moericke a. Pediatr Blood Cancer. 2013 Feb;60(2):344-8. doi: 10.1002/pbc.24354. Epub 2012 Sep 28. Pediatr Blood Cancer. 2013. PMID: 23024117 No abstract available.
Optimizing asparaginase therapy for acute lymphoblastic leukemia.
Rizzari C, Conter V, Starý J, Colombini A, Moericke A, Schrappe M. Rizzari C, et al. Among authors: moericke a. Curr Opin Oncol. 2013 Mar;25 Suppl 1:S1-9. doi: 10.1097/CCO.0b013e32835d7d85. Curr Opin Oncol. 2013. PMID: 23380829 Review.
24 results