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Rare Antagonistic Leptin Variants and Severe, Early-Onset Obesity.
Funcke JB, Moepps B, Roos J, von Schnurbein J, Verstraete K, Fröhlich-Reiterer E, Kohlsdorf K, Nunziata A, Brandt S, Tsirigotaki A, Dansercoer A, Suppan E, Haris B, Debatin KM, Savvides SN, Farooqi IS, Hussain K, Gierschik P, Fischer-Posovszky P, Wabitsch M. Funcke JB, et al. Among authors: moepps b. N Engl J Med. 2023 Jun 15;388(24):2253-2261. doi: 10.1056/NEJMoa2204041. N Engl J Med. 2023. PMID: 37314706
Classification of Congenital Leptin Deficiency.
von Schnurbein J, Zorn S, Nunziata A, Brandt S, Moepps B, Funcke JB, Hussain K, Farooqi IS, Fischer-Posovszky P, Wabitsch M. von Schnurbein J, et al. Among authors: moepps b. J Clin Endocrinol Metab. 2024 Mar 12:dgae149. doi: 10.1210/clinem/dgae149. Online ahead of print. J Clin Endocrinol Metab. 2024. PMID: 38470203
Compound heterozygous variants in OTULIN are associated with fulminant atypical late-onset ORAS.
Zinngrebe J, Moepps B, Monecke T, Gierschik P, Schlichtig F, Barth TFE, Strauß G, Boldrin E, Posovszky C, Schulz A, Beringer O, Rieser E, Jacobsen EM, Lorenz MR, Schwarz K, Pannicke U, Walczak H, Niessing D, Schuetz C, Fischer-Posovszky P, Debatin KM. Zinngrebe J, et al. Among authors: moepps b. EMBO Mol Med. 2022 Mar 7;14(3):e14901. doi: 10.15252/emmm.202114901. Epub 2022 Feb 16. EMBO Mol Med. 2022. PMID: 35170849 Free PMC article.
Functional and Phenotypic Characteristics of Human Leptin Receptor Mutations.
Nunziata A, Funcke JB, Borck G, von Schnurbein J, Brandt S, Lennerz B, Moepps B, Gierschik P, Fischer-Posovszky P, Wabitsch M. Nunziata A, et al. Among authors: moepps b. J Endocr Soc. 2018 Sep 17;3(1):27-41. doi: 10.1210/js.2018-00123. eCollection 2019 Jan 1. J Endocr Soc. 2018. PMID: 30560226 Free PMC article. Review.
Estimated prevalence of potentially damaging variants in the leptin gene.
Nunziata A, Borck G, Funcke JB, Kohlsdorf K, Brandt S, Hinney A, Moepps B, Gierschik P, Debatin KM, Fischer-Posovszky P, Wabitsch M. Nunziata A, et al. Among authors: moepps b. Mol Cell Pediatr. 2017 Nov 3;4(1):10. doi: 10.1186/s40348-017-0074-x. Mol Cell Pediatr. 2017. PMID: 29101506 Free PMC article.
Measurement of immunofunctional leptin to detect and monitor patients with functional leptin deficiency.
Wabitsch M, Pridzun L, Ranke M, von Schnurbein J, Moss A, Brandt S, Kohlsdorf K, Moepps B, Schaab M, Funcke JB, Gierschik P, Fischer-Posovszky P, Flehmig B, Kratzsch J. Wabitsch M, et al. Among authors: moepps b. Eur J Endocrinol. 2017 Mar;176(3):315-322. doi: 10.1530/EJE-16-0821. Epub 2016 Dec 22. Eur J Endocrinol. 2017. PMID: 28007844 Free PMC article.
55 results