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An Exploratory Trial of EPI-589 in Amyotrophic Lateral Sclerosis (EPIC-ALS): Protocol for a Multicenter, Open-Labeled, 24-Week, Single-Group Study.
Haji S, Fujita K, Oki R, Osaki Y, Miyamoto R, Morino H, Nagano S, Atsuta N, Kanazawa Y, Matsumoto Y, Arisawa A, Kawai H, Sato Y, Sakaguchi S, Yagi K, Hamatani T, Kagimura T, Yanagawa H, Mochizuki H, Doyu M, Sobue G, Harada M, Izumi Y. Haji S, et al. Among authors: mochizuki h. JMIR Res Protoc. 2023 Jan 30;12:e42032. doi: 10.2196/42032. JMIR Res Protoc. 2023. PMID: 36716091 Free PMC article.
Increase of arginine dimethylation correlates with the progression and prognosis of ALS.
Ikenaka K, Atsuta N, Maeda Y, Hotta Y, Nakamura R, Kawai K, Yokoi D, Hirakawa A, Taniguchi A, Morita M, Mizoguchi K, Mochizuki H, Kimura K, Katsuno M, Sobue G. Ikenaka K, et al. Among authors: mochizuki h. Neurology. 2019 Apr 16;92(16):e1868-e1877. doi: 10.1212/WNL.0000000000007311. Epub 2019 Mar 13. Neurology. 2019. PMID: 30867270
Amyotrophic lateral sclerosis with speech apraxia, predominant upper motor neuron signs, and prominent iron accumulation in the frontal operculum and precentral gyrus.
Mitani TT, Beck G, Kido K, Yamashita R, Yonenobu Y, Ogawa T, Saeki C, Okuno T, Nagano S, Morii E, Hasegawa M, Saito Y, Murayama S, Mochizuki H. Mitani TT, et al. Among authors: mochizuki h. Neuropathology. 2021 Aug;41(4):324-331. doi: 10.1111/neup.12763. Epub 2021 Jul 4. Neuropathology. 2021. PMID: 34219295
Imaging of the nigrostriatal system for evaluating the preclinical phase of Parkinson's disease development: the utility of neuromelanin, diffusion MRI, and DAT-SPECT.
Takahashi H, Kashiwagi N, Arisawa A, Matsuo C, Kato H, Adachi H, Kajiyama Y, Mochizuki H, Tomiyama N. Takahashi H, et al. Among authors: mochizuki h. Br J Radiol. 2022 Feb 1;95(1130):20210837. doi: 10.1259/bjr.20210837. Epub 2021 Nov 26. Br J Radiol. 2022. PMID: 34808066 Free PMC article.
piRNA/PIWI Protein Complex as a Potential Biomarker in Sporadic Amyotrophic Lateral Sclerosis.
Abdelhamid RF, Ogawa K, Beck G, Ikenaka K, Takeuchi E, Yasumizu Y, Jinno J, Kimura Y, Baba K, Nagai Y, Okada Y, Saito Y, Murayama S, Mochizuki H, Nagano S. Abdelhamid RF, et al. Among authors: mochizuki h. Mol Neurobiol. 2022 Mar;59(3):1693-1705. doi: 10.1007/s12035-021-02686-2. Epub 2022 Jan 11. Mol Neurobiol. 2022. PMID: 35015250 Free PMC article.
Serum asymmetric dimethylarginine level correlates with the progression and prognosis of amyotrophic lateral sclerosis.
Ikenaka K, Maeda Y, Hotta Y, Nagano S, Yamada S, Ito D, Torii R, Kakuda K, Tatebe H, Atsuta N, Aguirre C, Kimura Y, Baba K, Tokuda T, Katsuno M, Kimura K, Sobue G, Mochizuki H. Ikenaka K, et al. Among authors: mochizuki h. Eur J Neurol. 2022 May;29(5):1410-1416. doi: 10.1111/ene.15254. Epub 2022 Feb 6. Eur J Neurol. 2022. PMID: 35128793 Free PMC article.
1,697 results