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Development and validation of the first consensus gene-expression signature of operational tolerance in kidney transplantation, incorporating adjustment for immunosuppressive drug therapy.
Christakoudi S, Runglall M, Mobillo P, Rebollo-Mesa I, Tsui TL, Nova-Lamperti E, Taube C, Norris S, Kamra Y, Hilton R, Augustine T, Bhandari S, Baker R, Berglund D, Carr S, Game D, Griffin S, Kalra PA, Lewis R, Mark PB, Marks SD, MacPhee I, McKane W, Mohaupt MG, Paz-Artal E, Kon SP, Serón D, Sinha MD, Tucker B, Viklický O, Stahl D, Lechler RI, Lord GM, Hernandez-Fuentes MP. Christakoudi S, et al. Among authors: mobillo p. EBioMedicine. 2020 Aug;58:102899. doi: 10.1016/j.ebiom.2020.102899. Epub 2020 Jul 21. EBioMedicine. 2020. PMID: 32707447 Free PMC article.
Steroid regulation: An overlooked aspect of tolerance and chronic rejection in kidney transplantation.
Christakoudi S, Runglall M, Mobillo P, Rebollo-Mesa I, Tsui TL, Nova-Lamperti E, Norris S, Kamra Y, Hilton R, Bhandari S, Baker R, Berglund D, Carr S, Game D, Griffin S, Kalra PA, Lewis R, Mark PB, Marks SD, Macphee I, McKane W, Mohaupt MG, Pararajasingam R, Kon SP, Serón D, Sinha M, Tucker B, Viklický O, Lechler RI, Lord GM, Stahl D, Hernandez-Fuentes MP. Christakoudi S, et al. Among authors: mobillo p. Mol Cell Endocrinol. 2018 Sep 15;473:205-216. doi: 10.1016/j.mce.2018.01.021. Epub 2018 Feb 7. Mol Cell Endocrinol. 2018. PMID: 29427591 Free article.
Development of a multivariable gene-expression signature targeting T-cell-mediated rejection in peripheral blood of kidney transplant recipients validated in cross-sectional and longitudinal samples.
Christakoudi S, Runglall M, Mobillo P, Tsui TL, Duff C, Domingo-Vila C, Kamra Y, Delaney F, Montero R, Spiridou A, Kassimatis T, Phin-Kon S, Tucker B, Farmer C, Strom TB, Lord GM, Rebollo-Mesa I, Stahl D, Sacks S, Hernandez-Fuentes MP, Chowdhury P. Christakoudi S, et al. Among authors: mobillo p. EBioMedicine. 2019 Mar;41:571-583. doi: 10.1016/j.ebiom.2019.01.060. Epub 2019 Mar 2. EBioMedicine. 2019. PMID: 30833191 Free PMC article.
Biomarkers of Tolerance in Kidney Transplantation: Are We Predicting Tolerance or Response to Immunosuppressive Treatment?
Rebollo-Mesa I, Nova-Lamperti E, Mobillo P, Runglall M, Christakoudi S, Norris S, Smallcombe N, Kamra Y, Hilton R; Indices of Tolerance EU Consortium; Bhandari S, Baker R, Berglund D, Carr S, Game D, Griffin S, Kalra PA, Lewis R, Mark PB, Marks S, Macphee I, McKane W, Mohaupt MG, Pararajasingam R, Kon SP, Serón D, Sinha MD, Tucker B, Viklický O, Lechler RI, Lord GM, Hernandez-Fuentes MP. Rebollo-Mesa I, et al. Among authors: mobillo p. Am J Transplant. 2016 Dec;16(12):3443-3457. doi: 10.1111/ajt.13932. Epub 2016 Aug 8. Am J Transplant. 2016. PMID: 27328267 Free PMC article.
Increased CD40 Ligation and Reduced BCR Signalling Leads to Higher IL-10 Production in B Cells From Tolerant Kidney Transplant Patients.
Nova-Lamperti E, Chana P, Mobillo P, Runglall M, Kamra Y, McGregor R, Lord GM, Lechler RI, Lombardi G, Hernandez-Fuentes MP; GAMBIT Study. Nova-Lamperti E, et al. Among authors: mobillo p. Transplantation. 2017 Mar;101(3):541-547. doi: 10.1097/TP.0000000000001341. Transplantation. 2017. PMID: 27472092 Free PMC article.
Reduced TCR Signaling Contributes to Impaired Th17 Responses in Tolerant Kidney Transplant Recipients.
Nova-Lamperti E, Romano M, Christakoudi S, Runglall M, McGregor R, Mobillo P, Kamra Y, Tsui TL, Norris S, John S, Boardman DA, Lechler RI, Lombardi G, Hernandez-Fuentes MP; www.GAMBITstudy.co.uk. Nova-Lamperti E, et al. Among authors: mobillo p. Transplantation. 2018 Jan;102(1):e10-e17. doi: 10.1097/TP.0000000000001920. Transplantation. 2018. PMID: 28902773 Free PMC article.
Erratum to: Methods for evaluating medical tests and biomarkers.
Gopalakrishna G, Langendam M, Scholten R, Bossuyt P, Leeflang M, Noel-Storr A, Thomas J, Marshall I, Wallace B, Whiting P, Davenport C, Leeflang M, GopalaKrishna G, de Salis I, Mallett S, Wolff R, Whiting P, Riley R, Westwood M, Kleinen J, Collins G, Reitsma H, Moons K, Zapf A, Hoyer A, Kramer K, Kuss O, Ensor J, Deeks JJ, Martin EC, Riley RD, Rücker G, Steinhauser S, Schumacher M, Riley R, Ensor J, Snell K, Willis B, Debray T, Moons K, Deeks J, Collins G, di Ruffano LF, Willis B, Davenport C, Mallett S, Taylor-Phillips S, Hyde C, Deeks J, Mallett S, Taylor SA, Batnagar G; STREAMLINE COLON Investigators; STREAMLINE LUNG Investigators; METRIC Investigators; Taylor-Phillips S, Di Ruffano LF, Seedat F, Clarke A, Deeks J, Byron S, Nixon F, Albrow R, Walker T, Deakin C, Hyde C, Zhelev Z, Hunt H, di Ruffano LF, Yang Y, Abel L, Buchanan J, Fanshawe T, Shinkins B, Wynants L, Verbakel J, Van Huffel S, Timmerman D, Van Calster B, Leeflang M, Zwinderman A, Bossuyt P, Oke J, O'Sullivan J, Perera R, Nicholson B, Bromley HL, Roberts TE, Francis A, Petrie D, Mann GB, Malottki K, Smith H, Deeks J, Billingham L, Sitch A, Mallett S, Deeks J, Gerke O, Holm-Vilstrup M, Segtnan EA, Halekoh U, Høilund-… See abstract for full author list ➔ Gopalakrishna G, et al. Among authors: mobillo p. Diagn Progn Res. 2017 Mar 30;1:11. doi: 10.1186/s41512-017-0011-4. eCollection 2017. Diagn Progn Res. 2017. PMID: 31095132 Free PMC article.