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Tissue inhibitor of metalloproteinase (TIMP)-2 acts synergistically with synthetic matrix metalloproteinase (MMP) inhibitors but not with TIMP-4 to enhance the (Membrane type 1)-MMP-dependent activation of pro-MMP-2.
Toth M, Bernardo MM, Gervasi DC, Soloway PD, Wang Z, Bigg HF, Overall CM, DeClerck YA, Tschesche H, Cher ML, Brown S, Mobashery S, Fridman R. Toth M, et al. Among authors: mobashery s. J Biol Chem. 2000 Dec 29;275(52):41415-23. doi: 10.1074/jbc.M006871200. J Biol Chem. 2000. PMID: 10998420 Free article.
Complex pattern of membrane type 1 matrix metalloproteinase shedding. Regulation by autocatalytic cells surface inactivation of active enzyme.
Toth M, Hernandez-Barrantes S, Osenkowski P, Bernardo MM, Gervasi DC, Shimura Y, Meroueh O, Kotra LP, Gálvez BG, Arroyo AG, Mobashery S, Fridman R. Toth M, et al. Among authors: mobashery s. J Biol Chem. 2002 Jul 19;277(29):26340-50. doi: 10.1074/jbc.M200655200. Epub 2002 May 9. J Biol Chem. 2002. PMID: 12004057 Free article.
334 results