Mkrtichyan M - Search Results

1

MEK inhibition reprograms CD8⁺ T lymphocytes into memory stem cells with potent antitumor effects.

Verma V, Jafarzadeh N, Boi S, Kundu S, Jiang Z, Fan Y, Lopez J, Nandre R, Zeng P, Alolaqi F, Ahmad S, Gaur P, Barry ST, Valge-Archer VE, Smith PD, Banchereau J, Mkrtichyan M, Youngblood B, Rodriguez PC, Gupta S, Khleif SN. Verma V, et al. Among authors: mkrtichyan m. Nat Immunol. 2021 Jan;22(1):53-66. doi: 10.1038/s41590-020-00818-9. Epub 2020 Nov 23. Nat Immunol. 2021. PMID: 33230330 Free PMC article.

2

Anti-PD-1 synergizes with cyclophosphamide to induce potent anti-tumor vaccine effects through novel mechanisms.

Mkrtichyan M, Najjar YG, Raulfs EC, Abdalla MY, Samara R, Rotem-Yehudar R, Cook L, Khleif SN. Mkrtichyan M, et al. Eur J Immunol. 2011 Oct;41(10):2977-86. doi: 10.1002/eji.201141639. Epub 2011 Aug 17. Eur J Immunol. 2011. PMID: 21710477 Free PMC article.

3

B7-DC-Ig enhances vaccine effect by a novel mechanism dependent on PD-1 expression level on T cell subsets.

Mkrtichyan M, Najjar YG, Raulfs EC, Liu L, Langerman S, Guittard G, Ozbun L, Khleif SN. Mkrtichyan M, et al. J Immunol. 2012 Sep 1;189(5):2338-47. doi: 10.4049/jimmunol.1103085. Epub 2012 Jul 25. J Immunol. 2012. PMID: 22837483 Free PMC article.

4

Anti-PD-1 antibody significantly increases therapeutic efficacy of Listeria monocytogenes (Lm)-LLO immunotherapy.

Mkrtichyan M, Chong N, Abu Eid R, Wallecha A, Singh R, Rothman J, Khleif SN. Mkrtichyan M, et al. J Immunother Cancer. 2013 Aug 29;1:15. doi: 10.1186/2051-1426-1-15. eCollection 2013. J Immunother Cancer. 2013. PMID: 24829751 Free PMC article.

5

Selective inhibition of regulatory T cells by targeting the PI3K-Akt pathway.

Abu-Eid R, Samara RN, Ozbun L, Abdalla MY, Berzofsky JA, Friedman KM, Mkrtichyan M, Khleif SN. Abu-Eid R, et al. Among authors: mkrtichyan m. Cancer Immunol Res. 2014 Nov;2(11):1080-9. doi: 10.1158/2326-6066.CIR-14-0095. Epub 2014 Jul 30. Cancer Immunol Res. 2014. PMID: 25080445 Free PMC article.

6

Akt1 and -2 inhibition diminishes terminal differentiation and enhances central memory CD8⁺ T-cell proliferation and survival.

Abu Eid R, Friedman KM, Mkrtichyan M, Walens A, King W, Janik J, Khleif SN. Abu Eid R, et al. Among authors: mkrtichyan m. Oncoimmunology. 2015 Feb 3;4(5):e1005448. doi: 10.1080/2162402X.2015.1005448. eCollection 2015 May. Oncoimmunology. 2015. PMID: 26155399 Free PMC article.

7

Programmed death-1 & its ligands: promising targets for cancer immunotherapy.

Shrimali RK, Janik JE, Abu-Eid R, Mkrtichyan M, Khleif SN. Shrimali RK, et al. Among authors: mkrtichyan m. Immunotherapy. 2015;7(7):777-92. doi: 10.2217/imt.15.49. Epub 2015 Aug 7. Immunotherapy. 2015. PMID: 26250412 Review.

8

Mutant KRAS Conversion of Conventional T Cells into Regulatory T Cells.

Zdanov S, Mandapathil M, Abu Eid R, Adamson-Fadeyi S, Wilson W, Qian J, Carnie A, Tarasova N, Mkrtichyan M, Berzofsky JA, Whiteside TL, Khleif SN. Zdanov S, et al. Among authors: mkrtichyan m. Cancer Immunol Res. 2016 Apr;4(4):354-65. doi: 10.1158/2326-6066.CIR-15-0241. Epub 2016 Feb 15. Cancer Immunol Res. 2016. PMID: 26880715 Free PMC article.

9

Old-School Chemotherapy in Immunotherapeutic Combination in Cancer, A Low-cost Drug Repurposed.

Abu Eid R, Razavi GS, Mkrtichyan M, Janik J, Khleif SN. Abu Eid R, et al. Among authors: mkrtichyan m. Cancer Immunol Res. 2016 May;4(5):377-82. doi: 10.1158/2326-6066.CIR-16-0048. Epub 2016 May 1. Cancer Immunol Res. 2016. PMID: 27196429 Review.

10

Differential PI3Kδ Signaling in CD4⁺ T-cell Subsets Enables Selective Targeting of T Regulatory Cells to Enhance Cancer Immunotherapy.

Ahmad S, Abu-Eid R, Shrimali R, Webb M, Verma V, Doroodchi A, Berrong Z, Samara R, Rodriguez PC, Mkrtichyan M, Khleif SN. Ahmad S, et al. Among authors: mkrtichyan m. Cancer Res. 2017 Apr 15;77(8):1892-1904. doi: 10.1158/0008-5472.CAN-16-1839. Epub 2017 Jan 20. Cancer Res. 2017. PMID: 28108509

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