Mizushina Y - Search Results

1

Structural analysis of epolactaene derivatives as DNA polymerase inhibitors and anti-inflammatory compounds.

Mizushina Y, Kuramochi K, Ikawa H, Kuriyama I, Shimazaki N, Takemura M, Oshige M, Yoshida H, Koiwai O, Sugawara F, Kobayashi S, Sakaguchi K. Mizushina Y, et al. Int J Mol Med. 2005 May;15(5):785-93. Int J Mol Med. 2005. PMID: 15806299

2

A plant phytotoxin, solanapyrone A, is an inhibitor of DNA polymerase beta and lambda.

Mizushina Y, Kamisuki S, Kasai N, Shimazaki N, Takemura M, Asahara H, Linn S, Yoshida S, Matsukage A, Koiwai O, Sugawara F, Yoshida H, Sakaguchi K. Mizushina Y, et al. J Biol Chem. 2002 Jan 4;277(1):630-8. doi: 10.1074/jbc.M105144200. Epub 2001 Oct 24. J Biol Chem. 2002. PMID: 11677229 Free article.

3

Novel anti-inflammatory compounds from Rubus sieboldii, triterpenoids, are inhibitors of mammalian DNA polymerases.

Murakami C, Ishijima K, Hirota M, Sakaguchi K, Yoshida H, Mizushina Y. Murakami C, et al. Among authors: mizushina y. Biochim Biophys Acta. 2002 Apr 29;1596(2):193-200. doi: 10.1016/s0167-4838(02)00227-3. Biochim Biophys Acta. 2002. PMID: 12007601

4

A sulphoquinovosyl diacylglycerol is a DNA polymerase epsilon inhibitor.

Mizushina Y, Xu X, Asahara H, Takeuchi R, Oshige M, Shimazaki N, Takemura M, Yamaguchi T, Kuroda K, Linn S, Yoshida H, Koiwai O, Saneyoshi M, Sugawara F, Sakaguchi K. Mizushina Y, et al. Biochem J. 2003 Feb 15;370(Pt 1):299-305. doi: 10.1042/BJ20021737. Biochem J. 2003. PMID: 12435270 Free PMC article.

5

Some anti-chronic inflammatory compounds are DNA polymerase lambda-specific inhibitors.

Mizushina Y, Hirota M, Murakami C, Ishidoh T, Kamisuki S, Shimazaki N, Takemura M, Perpelescu M, Suzuki M, Yoshida H, Sugawara F, Koiwai O, Sakaguchi K. Mizushina Y, et al. Biochem Pharmacol. 2003 Nov 15;66(10):1935-44. doi: 10.1016/s0006-2952(03)00551-3. Biochem Pharmacol. 2003. PMID: 14599551

6

Structure-activity relationships of epolactaene analogs as DNA polymerases inhibitors.

Kuramochi K, Mizushina Y, Nagata S, Sugawara F, Sakaguchi K, Kobayashi S. Kuramochi K, et al. Among authors: mizushina y. Bioorg Med Chem. 2004 May 1;12(9):1983-9. doi: 10.1016/j.bmc.2004.03.007. Bioorg Med Chem. 2004. PMID: 15080901

7

Structural relationship of lithocholic acid derivatives binding to the N-terminal 8-kDa domain of DNA polymerase beta.

Mizushina Y, Kasai N, Miura K, Hanashima S, Takemura M, Yoshida H, Sugawara F, Sakaguchi K. Mizushina Y, et al. Biochemistry. 2004 Aug 24;43(33):10669-77. doi: 10.1021/bi049307r. Biochemistry. 2004. PMID: 15311928

We reported previously that lithocholic acid (LCA, 3-alpha-hydroxy-5-beta-cholan-24-oic acid), one of the major compounds in the secondary bile acids, selectively inhibited the activity of mammalian DNA polymerase beta (pol beta) [Mizushina, Y., Ohkubo, T., Sugawara …

We reported previously that lithocholic acid (LCA, 3-alpha-hydroxy-5-beta-cholan-24-oic acid), one of the major compounds in the secondary b …

8

Inhibitory action of conjugated C18-fatty acids on DNA polymerases and DNA topoisomerases.

Mizushina Y, Tsuzuki T, Eitsuka T, Miyazawa T, Kobayashi K, Ikawa H, Kuriyama I, Yonezawa Y, Takemura M, Yoshida H, Sakaguchi K. Mizushina Y, et al. Lipids. 2004 Oct;39(10):977-83. doi: 10.1007/s11745-004-1319-y. Lipids. 2004. PMID: 15691019

9

Dipeptide alcohol-based inhibitors of eukaryotic DNA polymerase alpha.

Kuriyama I, Asano N, Kato I, Ikeda K, Takemura M, Yoshida H, Sakaguchi K, Mizushina Y. Kuriyama I, et al. Among authors: mizushina y. Bioorg Med Chem. 2005 Mar 15;13(6):2187-96. doi: 10.1016/j.bmc.2004.12.052. Bioorg Med Chem. 2005. PMID: 15727871

10

Structural analysis of isosteviol and related compounds as DNA polymerase and DNA topoisomerase inhibitors.

Mizushina Y, Akihisa T, Ukiya M, Hamasaki Y, Murakami-Nakai C, Kuriyama I, Takeuchi T, Sugawara F, Yoshida H. Mizushina Y, et al. Life Sci. 2005 Sep 9;77(17):2127-40. doi: 10.1016/j.lfs.2005.03.022. Life Sci. 2005. PMID: 15935396

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