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A chemoproteoinformatics approach demonstrates that aspirin increases sensitivity to MEK inhibition by directly binding to RPS5.
Watanabe M, Boku S, Kobayashi K, Kurumida Y, Sukeno M, Masuda M, Mizushima K, Kato C, Iizumi Y, Hirota K, Naito Y, Mutoh M, Kameda T, Sakai T. Watanabe M, et al. Among authors: mizushima k. PNAS Nexus. 2022 May 16;1(2):pgac059. doi: 10.1093/pnasnexus/pgac059. eCollection 2022 May. PNAS Nexus. 2022. PMID: 36713317 Free PMC article.
Bofutsushosan, an Oriental Herbal Medicine, Attenuates the Weight Gain of White Adipose Tissue and the Increased Size of Adipocytes Associated with the Increase in Their Expression of Uncoupling Protein 1 in High-Fat Diet-Fed Male KK/Ta mice.
Akagiri S, Naito Y, Ichikawa H, Mizushima K, Takagi T, Handa O, Kokura S, Yoshikawa T. Akagiri S, et al. Among authors: mizushima k. J Clin Biochem Nutr. 2008 Mar;42(2):158-66. doi: 10.3164/jcbn.2008023. J Clin Biochem Nutr. 2008. PMID: 18385834 Free PMC article.
Lansoprazole, a proton pump inhibitor, mediates anti-inflammatory effect in gastric mucosal cells through the induction of heme oxygenase-1 via activation of NF-E2-related factor 2 and oxidation of kelch-like ECH-associating protein 1.
Takagi T, Naito Y, Okada H, Ishii T, Mizushima K, Akagiri S, Adachi S, Handa O, Kokura S, Ichikawa H, Itoh K, Yamamoto M, Matsui H, Yoshikawa T. Takagi T, et al. Among authors: mizushima k. J Pharmacol Exp Ther. 2009 Oct;331(1):255-64. doi: 10.1124/jpet.109.152702. Epub 2009 Jul 23. J Pharmacol Exp Ther. 2009. PMID: 19628634
240 results