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Apixaban, an orally available anticoagulant, inhibits SARS-CoV-2 replication and its major protease in a non-competitive way.
Chaves OA, Sacramento CQ, Fintelman-Rodrigues N, Temerozo JR, Pereira-Dutra F, Mizurini DM, Monteiro RQ, Vazquez L, Bozza PT, Castro-Faria-Neto HC, Souza TML. Chaves OA, et al. Among authors: mizurini dm. J Mol Cell Biol. 2022 Sep 21;14(6):mjac039. doi: 10.1093/jmcb/mjac039. J Mol Cell Biol. 2022. PMID: 35759391 Free PMC article. No abstract available.
Plasma Peptidylarginine Deiminase IV Promotes VWF-Platelet String Formation and Accelerates Thrombosis After Vessel Injury.
Sorvillo N, Mizurini DM, Coxon C, Martinod K, Tilvawala R, Cherpokova D, Salinger AJ, Seward RJ, Staudinger C, Weerapana E, Shapiro NI, Costello CE, Thompson PR, Wagner DD. Sorvillo N, et al. Among authors: mizurini dm. Circ Res. 2019 Aug 16;125(5):507-519. doi: 10.1161/CIRCRESAHA.118.314571. Epub 2019 Jun 28. Circ Res. 2019. PMID: 31248335 Free PMC article.
Ixonnexin from Tick Saliva Promotes Fibrinolysis by Interacting with Plasminogen and Tissue-Type Plasminogen Activator, and Prevents Arterial Thrombosis.
Assumpção TC, Mizurini DM, Ma D, Monteiro RQ, Ahlstedt S, Reyes M, Kotsyfakis M, Mather TN, Andersen JF, Lukszo J, Ribeiro JMC, Francischetti IMB. Assumpção TC, et al. Among authors: mizurini dm. Sci Rep. 2018 Mar 19;8(1):4806. doi: 10.1038/s41598-018-22780-1. Sci Rep. 2018. PMID: 29555911 Free PMC article.
Evoking picomolar binding in RNA by a single phosphorodithioate linkage.
Abeydeera ND, Egli M, Cox N, Mercier K, Conde JN, Pallan PS, Mizurini DM, Sierant M, Hibti FE, Hassell T, Wang T, Liu FW, Liu HM, Martinez C, Sood AK, Lybrand TP, Frydman C, Monteiro RQ, Gomer RH, Nawrot B, Yang X. Abeydeera ND, et al. Among authors: mizurini dm. Nucleic Acids Res. 2016 Sep 30;44(17):8052-64. doi: 10.1093/nar/gkw725. Epub 2016 Aug 26. Nucleic Acids Res. 2016. PMID: 27566147 Free PMC article.
In Vitro Mode of Action and Anti-thrombotic Activity of Boophilin, a Multifunctional Kunitz Protease Inhibitor from the Midgut of a Tick Vector of Babesiosis, Rhipicephalus microplus.
Assumpção TC, Ma D, Mizurini DM, Kini RM, Ribeiro JM, Kotsyfakis M, Monteiro RQ, Francischetti IM. Assumpção TC, et al. Among authors: mizurini dm. PLoS Negl Trop Dis. 2016 Jan 8;10(1):e0004298. doi: 10.1371/journal.pntd.0004298. eCollection 2016 Jan. PLoS Negl Trop Dis. 2016. PMID: 26745503 Free PMC article.
22 results