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Intranasal vaccination with HBs and HBc protein combined with carboxyl vinyl polymer induces strong neutralizing antibody, anti-HBs IgA, and IFNG response.
Sanada T, Yamamoto N, Kayesh MEH, Tsukiyama-Kohara K, Hasegawa H, Miyazaki T, Takano JI, Shiogama Y, Yasutomi Y, Goh Y, Yoshida O, Hiasa Y, Kohara M. Sanada T, et al. Among authors: miyazaki t. Biochem Biophys Res Commun. 2019 Nov 26;520(1):86-92. doi: 10.1016/j.bbrc.2019.09.072. Epub 2019 Sep 30. Biochem Biophys Res Commun. 2019. PMID: 31582218 Free article.
Intranasal therapeutic vaccine containing HBsAg and HBcAg for patients with chronic hepatitis B; 18 months follow-up results of phase IIa clinical study.
Yoshida O, Akbar SMF, Imai Y, Sanada T, Tsukiyama-Kohara K, Miyazaki T, Kamishita T, Miyake T, Tokumoto Y, Hikita H, Tsuge M, Shimizu M, Al Mahtab M, Aguilar JC, Guillen G, Kohara M, Hiasa Y. Yoshida O, et al. Among authors: miyazaki t. Hepatol Res. 2023 Mar;53(3):196-207. doi: 10.1111/hepr.13851. Epub 2022 Nov 18. Hepatol Res. 2023. PMID: 36399406
Intranasal HBsAg/HBcAg-Containing Vaccine Induces Neutralizing Anti-HBs Production in Hepatitis B Vaccine Non-Responders.
Shiraishi K, Yoshida O, Imai Y, Akbar SMF, Sanada T, Kohara M, Miyazaki T, Kamishita T, Miyake T, Hirooka M, Tokumoto Y, Abe M, Rubido JCA, Nieto GG, Hiasa Y. Shiraishi K, et al. Among authors: miyazaki t. Vaccines (Basel). 2023 Sep 12;11(9):1479. doi: 10.3390/vaccines11091479. Vaccines (Basel). 2023. PMID: 37766155 Free PMC article.
Biodistribution assessment of cationic pullulan nanogel, a nasal vaccine delivery system, in mice and non-human primates.
Yuki Y, Harada N, Sawada SI, Uchida Y, Nakahashi-Ouchida R, Mori H, Yamanoue T, Machita T, Kanazawa M, Fukumoto D, Ohba H, Miyazaki T, Akiyoshi K, Fujihashi K, Kiyono H. Yuki Y, et al. Among authors: miyazaki t. Vaccine. 2023 Jul 31;41(34):4941-4949. doi: 10.1016/j.vaccine.2023.06.065. Epub 2023 Jun 27. Vaccine. 2023. PMID: 37385890 Free article.
A nanogel-based trivalent PspA nasal vaccine protects macaques from intratracheal challenge with pneumococci.
Nakahashi-Ouchida R, Uchida Y, Yuki Y, Katakai Y, Yamanoue T, Ogawa H, Munesue Y, Nakano N, Hanari K, Miyazaki T, Saito Y, Umemoto S, Sawada SI, Mukerji R, Briles DE, Yasutomi Y, Akiyoshi K, Kiyono H. Nakahashi-Ouchida R, et al. Among authors: miyazaki t. Vaccine. 2021 Jun 8;39(25):3353-3364. doi: 10.1016/j.vaccine.2021.04.069. Epub 2021 May 17. Vaccine. 2021. PMID: 34016473 Free article.
4,201 results