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Anti-apoptotic molecule Bcl-2 regulates the differentiation, activation, and survival of both osteoblasts and osteoclasts.
Nagase Y, Iwasawa M, Akiyama T, Kadono Y, Nakamura M, Oshima Y, Yasui T, Matsumoto T, Hirose J, Nakamura H, Miyamoto T, Bouillet P, Nakamura K, Tanaka S. Nagase Y, et al. Among authors: miyamoto t. J Biol Chem. 2009 Dec 25;284(52):36659-36669. doi: 10.1074/jbc.M109.016915. Epub 2009 Oct 21. J Biol Chem. 2009. PMID: 19846553 Free PMC article.
Identification of Nedd9 as a TGF-β-Smad2/3 Target Gene Involved in RANKL-Induced Osteoclastogenesis by Comprehensive Analysis.
Omata Y, Nakamura S, Koyama T, Yasui T, Hirose J, Izawa N, Matsumoto T, Imai Y, Seo S, Kurokawa M, Tsutsumi S, Kadono Y, Morimoto C, Aburatani H, Miyamoto T, Tanaka S. Omata Y, et al. Among authors: miyamoto t. PLoS One. 2016 Jun 23;11(6):e0157992. doi: 10.1371/journal.pone.0157992. eCollection 2016. PLoS One. 2016. PMID: 27336669 Free PMC article.
Smad4 is required to inhibit osteoclastogenesis and maintain bone mass.
Morita M, Yoshida S, Iwasaki R, Yasui T, Sato Y, Kobayashi T, Watanabe R, Oike T, Miyamoto K, Takami M, Ozato K, Deng CX, Aburatani H, Tanaka S, Yoshimura A, Toyama Y, Matsumoto M, Nakamura M, Kawana H, Nakagawa T, Miyamoto T. Morita M, et al. Among authors: miyamoto t, miyamoto k. Sci Rep. 2016 Oct 12;6:35221. doi: 10.1038/srep35221. Sci Rep. 2016. PMID: 27731422 Free PMC article.
Negative feedback loop of bone resorption by NFATc1-dependent induction of Cadm1.
Nakamura S, Koyama T, Izawa N, Nomura S, Fujita T, Omata Y, Minami T, Matsumoto M, Nakamura M, Fujita-Jimbo E, Momoi T, Miyamoto T, Aburatani H, Tanaka S. Nakamura S, et al. Among authors: miyamoto t. PLoS One. 2017 Apr 17;12(4):e0175632. doi: 10.1371/journal.pone.0175632. eCollection 2017. PLoS One. 2017. PMID: 28414795 Free PMC article.
Metabolomics-based profiles predictive of low bone mass in menopausal women.
Miyamoto T, Hirayama A, Sato Y, Koboyashi T, Katsuyama E, Kanagawa H, Fujie A, Morita M, Watanabe R, Tando T, Miyamoto K, Tsuji T, Funayama A, Soga T, Tomita M, Nakamura M, Matsumoto M. Miyamoto T, et al. Among authors: miyamoto k. Bone Rep. 2018 Jun 18;9:11-18. doi: 10.1016/j.bonr.2018.06.004. eCollection 2018 Dec. Bone Rep. 2018. PMID: 29955645 Free PMC article.
CTLA4-Ig Directly Inhibits Osteoclastogenesis by Interfering With Intracellular Calcium Oscillations in Bone Marrow Macrophages.
Okada H, Kajiya H, Omata Y, Matsumoto T, Sato Y, Kobayashi T, Nakamura S, Kaneko Y, Nakamura S, Koyama T, Sudo S, Shin M, Okamoto F, Watanabe H, Tachibana N, Hirose J, Saito T, Takai T, Matsumoto M, Nakamura M, Okabe K, Miyamoto T, Tanaka S. Okada H, et al. Among authors: miyamoto t. J Bone Miner Res. 2019 Sep;34(9):1744-1752. doi: 10.1002/jbmr.3754. Epub 2019 Jul 16. J Bone Miner Res. 2019. PMID: 31067348 Free article.
4,110 results