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Fibroblast growth factor 18 stimulates the proliferation of hepatic stellate cells, thereby inducing liver fibrosis.
Tsuchiya Y, Seki T, Kobayashi K, Komazawa-Sakon S, Shichino S, Nishina T, Fukuhara K, Ikejima K, Nagai H, Igarashi Y, Ueha S, Oikawa A, Tsurusaki S, Yamazaki S, Nishiyama C, Mikami T, Yagita H, Okumura K, Kido T, Miyajima A, Matsushima K, Imasaka M, Araki K, Imamura T, Ohmuraya M, Tanaka M, Nakano H. Tsuchiya Y, et al. Among authors: miyajima a. Nat Commun. 2023 Oct 9;14(1):6304. doi: 10.1038/s41467-023-42058-z. Nat Commun. 2023. PMID: 37813881 Free PMC article.
Transcriptomic and proteomic studies suggest the establishment of advanced zonation-like profiles in human-induced pluripotent stem cell-derived liver sinusoidal endothelial cells and carboxypeptidase M-positive liver progenitor cells cocultured in a fluidic microenvironment.
Danoy M, Poulain S, Jellali R, Scheidecker B, Tauran Y, Leduc M, Bruce J, Kim SH, Kido T, Miyajima A, Sakai Y, Leclerc E. Danoy M, et al. Among authors: miyajima a. Hepatol Res. 2023 Jul;53(7):661-674. doi: 10.1111/hepr.13893. Epub 2023 Apr 2. Hepatol Res. 2023. PMID: 36866738
Analysis of distribution, collection, and confirmation of capacity dependency of small extracellular vesicles toward a therapy for liver cirrhosis.
Takeda N, Tsuchiya A, Mito M, Natsui K, Natusi Y, Koseki Y, Tomiyoshi K, Yamazaki F, Yoshida Y, Abe H, Sano M, Kido T, Yoshioka Y, Kikuta J, Itoh T, Nishimura K, Ishii M, Ochiya T, Miyajima A, Terai S. Takeda N, et al. Among authors: miyajima a. Inflamm Regen. 2023 Oct 9;43(1):48. doi: 10.1186/s41232-023-00299-x. Inflamm Regen. 2023. PMID: 37814342 Free PMC article.
Unique lipid composition maintained by extracellular blockade leads to prooncogenicity.
Kudo K, Yanagiya R, Hasegawa M, Carreras J, Miki Y, Nakayama S, Nagashima E, Miyatake Y, Torii K, Ando K, Nakamura N, Miyajima A, Murakami M, Kotani A. Kudo K, et al. Among authors: miyajima a. Cell Death Discov. 2024 May 8;10(1):221. doi: 10.1038/s41420-024-01971-y. Cell Death Discov. 2024. PMID: 38719806 Free PMC article.
721 results