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Short-term TNFα shedding is independent of cytoplasmic phosphorylation or furin cleavage of ADAM17.
Schwarz J, Broder C, Helmstetter A, Schmidt S, Yan I, Müller M, Schmidt-Arras D, Becker-Pauly C, Koch-Nolte F, Mittrücker HW, Rabe B, Rose-John S, Chalaris A. Schwarz J, et al. Among authors: mittrucker hw. Biochim Biophys Acta. 2013 Dec;1833(12):3355-3367. doi: 10.1016/j.bbamcr.2013.10.005. Epub 2013 Oct 14. Biochim Biophys Acta. 2013. PMID: 24135057 Free article.
Inflammation-Induced IL-6 Functions as a Natural Brake on Macrophages and Limits GN.
Luig M, Kluger MA, Goerke B, Meyer M, Nosko A, Yan I, Scheller J, Mittrücker HW, Rose-John S, Stahl RA, Panzer U, Steinmetz OM. Luig M, et al. Among authors: mittrucker hw. J Am Soc Nephrol. 2015 Jul;26(7):1597-607. doi: 10.1681/ASN.2014060620. Epub 2015 Feb 5. J Am Soc Nephrol. 2015. PMID: 25655068 Free PMC article.
IL-23 prevents IL-13-dependent tissue repair associated with Ly6C(lo) monocytes in Entamoeba histolytica-induced liver damage.
Noll J, Helk E, Fehling H, Bernin H, Marggraff C, Jacobs T, Huber S, Pelczar P, Ernst T, Ittrich H, Otto B, Mittrücker HW, Hölscher C, Tacke F, Bruchhaus I, Tannich E, Lotter H. Noll J, et al. Among authors: mittrucker hw. J Hepatol. 2016 May;64(5):1147-1157. doi: 10.1016/j.jhep.2016.01.013. Epub 2016 Jan 22. J Hepatol. 2016. PMID: 26809113 Free article.
IL-6 trans-signaling is essential for the development of hepatocellular carcinoma in mice.
Bergmann J, Müller M, Baumann N, Reichert M, Heneweer C, Bolik J, Lücke K, Gruber S, Carambia A, Boretius S, Leuschner I, Becker T, Rabe B, Herkel J, Wunderlich FT, Mittrücker HW, Rose-John S, Schmidt-Arras D. Bergmann J, et al. Among authors: mittrucker hw. Hepatology. 2017 Jan;65(1):89-103. doi: 10.1002/hep.28874. Epub 2016 Nov 22. Hepatology. 2017. PMID: 27770462
The role of ADAM17 in the T-cell response against bacterial pathogens.
Link MA, Lücke K, Schmid J, Schumacher V, Eden T, Rose-John S, Mittrücker HW. Link MA, et al. Among authors: mittrucker hw. PLoS One. 2017 Sep 6;12(9):e0184320. doi: 10.1371/journal.pone.0184320. eCollection 2017. PLoS One. 2017. PMID: 28877252 Free PMC article.
Cell-autonomous hepatocyte-specific GP130 signaling is sufficient to trigger a robust innate immune response in mice.
Schumacher N, Yan K, Gandraß M, Müller M, Krisp C, Häsler R, Carambia A, Nofer JR, Bernardes JP, Khouja M, Thomsen I, Chalupsky K, Bolik J, Hölscher C, Wunderlich T, Herkel J, Rosenstiel P, Schramm C, Schlüter H, Renné T, Mittrücker HW, Rose-John S, Schmidt-Arras D. Schumacher N, et al. Among authors: mittrucker hw. J Hepatol. 2021 Feb;74(2):407-418. doi: 10.1016/j.jhep.2020.09.021. Epub 2020 Sep 25. J Hepatol. 2021. PMID: 32987028
147 results