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Fiber deprivation and microbiome-borne curli shift gut bacterial populations and accelerate disease in a mouse model of Parkinson's disease.
Schmit KJ, Garcia P, Sciortino A, Aho VTE, Pardo Rodriguez B, Thomas MH, Gérardy JJ, Bastero Acha I, Halder R, Cialini C, Heurtaux T, Ostahi I, Busi SB, Grandmougin L, Lowndes T, Singh Y, Martens EC, Mittelbronn M, Buttini M, Wilmes P. Schmit KJ, et al. Among authors: mittelbronn m. Cell Rep. 2023 Sep 26;42(9):113071. doi: 10.1016/j.celrep.2023.113071. Epub 2023 Sep 8. Cell Rep. 2023. PMID: 37676767 Free PMC article.
Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions.
Soriano-Baguet L, Grusdat M, Kurniawan H, Benzarti M, Binsfeld C, Ewen A, Longworth J, Bonetti L, Guerra L, Franchina DG, Kobayashi T, Horkova V, Verschueren C, Helgueta S, Gérard D, More TH, Henne A, Dostert C, Farinelle S, Lesur A, Gérardy JJ, Jäger C, Mittelbronn M, Sinkkonen L, Hiller K, Meiser J, Brenner D. Soriano-Baguet L, et al. Among authors: mittelbronn m. Cell Rep. 2023 Mar 28;42(3):112153. doi: 10.1016/j.celrep.2023.112153. Epub 2023 Feb 26. Cell Rep. 2023. PMID: 36848289 Free article.
Propagative α-synuclein seeds as serum biomarkers for synucleinopathies.
Okuzumi A, Hatano T, Matsumoto G, Nojiri S, Ueno SI, Imamichi-Tatano Y, Kimura H, Kakuta S, Kondo A, Fukuhara T, Li Y, Funayama M, Saiki S, Taniguchi D, Tsunemi T, McIntyre D, Gérardy JJ, Mittelbronn M, Kruger R, Uchiyama Y, Nukina N, Hattori N. Okuzumi A, et al. Among authors: mittelbronn m. Nat Med. 2023 Jun;29(6):1448-1455. doi: 10.1038/s41591-023-02358-9. Epub 2023 May 29. Nat Med. 2023. PMID: 37248302 Free PMC article.
Single-cell transcriptomics of NRAS-mutated melanoma transitioning to drug resistance reveals P2RX7 as an indicator of early drug response.
Randic T, Magni S, Philippidou D, Margue C, Grzyb K, Preis JR, Wroblewska JP, Nazarov PV, Mittelbronn M, Frauenknecht KBM, Skupin A, Kreis S. Randic T, et al. Among authors: mittelbronn m. Cell Rep. 2023 Jul 25;42(7):112696. doi: 10.1016/j.celrep.2023.112696. Epub 2023 Jun 29. Cell Rep. 2023. PMID: 37379213 Free article.
A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation.
Bonetti L, Horkova V, Longworth J, Guerra L, Kurniawan H, Franchina DG, Soriano-Baguet L, Grusdat M, Spath S, Koncina E, Ewen A, Binsfeld C, Verschueren C, Gérardy JJ, Kobayashi T, Dostert C, Farinelle S, Härm J, Chen Y, Harris IS, Lang PA, Vasiliou V, Waisman A, Letellier E, Becher B, Mittelbronn M, Brenner D. Bonetti L, et al. Among authors: mittelbronn m. bioRxiv [Preprint]. 2023 Jul 7:2023.07.06.547932. doi: 10.1101/2023.07.06.547932. bioRxiv. 2023. PMID: 37489135 Free PMC article. Preprint.
Blocking TGF-β- and Epithelial-to-Mesenchymal Transition (EMT)-mediated activation of vessel-associated mural cells in glioblastoma impacts tumor angiogenesis.
Merk L, Regel K, Eckhardt H, Evers M, El-Ayoubi A, Mittelbronn M, Krüger M, Gérardy JJ, Mack AF, Naumann U. Merk L, et al. Among authors: mittelbronn m. Free Neuropathol. 2024 Mar 1;5:5-4. doi: 10.17879/freeneuropathology-2024-5188. eCollection 2024 Jan. Free Neuropathol. 2024. PMID: 38455669 Free PMC article.
Actin cytoskeleton depolymerization increases matrix metalloproteinase gene expression in breast cancer cells by promoting translocation of cysteine-rich protein 2 to the nucleus.
Mgrditchian T, Brown-Clay J, Hoffmann C, Müller T, Filali L, Ockfen E, Mao X, Moreau F, Casellas CP, Kaoma T, Mittelbronn M, Thomas C. Mgrditchian T, et al. Among authors: mittelbronn m. Front Cell Dev Biol. 2023 May 15;11:1100938. doi: 10.3389/fcell.2023.1100938. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 37266453 Free PMC article.
337 results