Mitsuya H - Search Results

1

Efficacy of Antibodies and Antiviral Drugs against Covid-19 Omicron Variant.

Takashita E, Kinoshita N, Yamayoshi S, Sakai-Tagawa Y, Fujisaki S, Ito M, Iwatsuki-Horimoto K, Chiba S, Halfmann P, Nagai H, Saito M, Adachi E, Sullivan D, Pekosz A, Watanabe S, Maeda K, Imai M, Yotsuyanagi H, Mitsuya H, Ohmagari N, Takeda M, Hasegawa H, Kawaoka Y. Takashita E, et al. Among authors: mitsuya h. N Engl J Med. 2022 Mar 10;386(10):995-998. doi: 10.1056/NEJMc2119407. Epub 2022 Jan 26. N Engl J Med. 2022. PMID: 35081300 Free PMC article. No abstract available.

2

Identification of amino acid residues critical for LD78beta, a variant of human macrophage inflammatory protein-1alpha, binding to CCR5 and inhibition of R5 human immunodeficiency virus type 1 replication.

Miyakawa T, Obaru K, Maeda K, Harada S, Mitsuya H. Miyakawa T, et al. Among authors: mitsuya h. J Biol Chem. 2002 Feb 15;277(7):4649-55. doi: 10.1074/jbc.M109198200. Epub 2001 Dec 4. J Biol Chem. 2002. PMID: 11734558 Free article.

3

The current status of, and challenges in, the development of CCR5 inhibitors as therapeutics for HIV-1 infection.

Maeda K, Nakata H, Ogata H, Koh Y, Miyakawa T, Mitsuya H. Maeda K, et al. Among authors: mitsuya h. Curr Opin Pharmacol. 2004 Oct;4(5):447-52. doi: 10.1016/j.coph.2004.07.004. Curr Opin Pharmacol. 2004. PMID: 15351348 Review.

4

Development of therapeutics for AIDS: structure-based molecular targeting.

Maeda K, Mitsuya H. Maeda K, et al. Among authors: mitsuya h. Tuberculosis (Edinb). 2007 Aug;87 Suppl 1:S31-4. doi: 10.1016/j.tube.2007.05.009. Epub 2007 Jul 10. Tuberculosis (Edinb). 2007. PMID: 17625972 Review.

5

[Structure-guided molecular-targeting approach for development of AIDS therapeutics].

Maeda K, Mitsuya H. Maeda K, et al. Among authors: mitsuya h. Nihon Rinsho. 2010 Oct;68(10):1889-95. Nihon Rinsho. 2010. PMID: 20954335 Review. Japanese.

6

HIV-1 with HBV-associated Q151M substitution in RT becomes highly susceptible to entecavir: structural insights into HBV-RT inhibition by entecavir.

Yasutake Y, Hattori SI, Hayashi H, Matsuda K, Tamura N, Kohgo S, Maeda K, Mitsuya H. Yasutake Y, et al. Among authors: mitsuya h. Sci Rep. 2018 Jan 26;8(1):1624. doi: 10.1038/s41598-018-19602-9. Sci Rep. 2018. PMID: 29374261 Free PMC article.

7

The High Genetic Barrier of EFdA/MK-8591 Stems from Strong Interactions with the Active Site of Drug-Resistant HIV-1 Reverse Transcriptase.

Takamatsu Y, Das D, Kohgo S, Hayashi H, Delino NS, Sarafianos SG, Mitsuya H, Maeda K. Takamatsu Y, et al. Among authors: mitsuya h. Cell Chem Biol. 2018 Oct 18;25(10):1268-1278.e3. doi: 10.1016/j.chembiol.2018.07.014. Epub 2018 Aug 30. Cell Chem Biol. 2018. PMID: 30174310 Free PMC article.

8

Combination of a Latency-Reversing Agent With a Smac Mimetic Minimizes Secondary HIV-1 Infection in vitro.

Hattori SI, Matsuda K, Tsuchiya K, Gatanaga H, Oka S, Yoshimura K, Mitsuya H, Maeda K. Hattori SI, et al. Among authors: mitsuya h. Front Microbiol. 2018 Sep 19;9:2022. doi: 10.3389/fmicb.2018.02022. eCollection 2018. Front Microbiol. 2018. PMID: 30283406 Free PMC article.

9

Active-site deformation in the structure of HIV-1 RT with HBV-associated septuple amino acid substitutions rationalizes the differential susceptibility of HIV-1 and HBV against 4'-modified nucleoside RT inhibitors.

Yasutake Y, Hattori SI, Tamura N, Matsuda K, Kohgo S, Maeda K, Mitsuya H. Yasutake Y, et al. Among authors: mitsuya h. Biochem Biophys Res Commun. 2019 Feb 19;509(4):943-948. doi: 10.1016/j.bbrc.2019.01.026. Epub 2019 Jan 14. Biochem Biophys Res Commun. 2019. PMID: 30648556

10

Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine.

Yasutake Y, Hattori SI, Tamura N, Matsuda K, Kohgo S, Maeda K, Mitsuya H. Yasutake Y, et al. Among authors: mitsuya h. Sci Rep. 2020 Feb 20;10(1):3021. doi: 10.1038/s41598-020-59775-w. Sci Rep. 2020. PMID: 32080249 Free PMC article.

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