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A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replication.
Hattori SI, Higashi-Kuwata N, Hayashi H, Allu SR, Raghavaiah J, Bulut H, Das D, Anson BJ, Lendy EK, Takamatsu Y, Takamune N, Kishimoto N, Murayama K, Hasegawa K, Li M, Davis DA, Kodama EN, Yarchoan R, Wlodawer A, Misumi S, Mesecar AD, Ghosh AK, Mitsuya H. Hattori SI, et al. Among authors: mitsuya h. Nat Commun. 2021 Jan 28;12(1):668. doi: 10.1038/s41467-021-20900-6. Nat Commun. 2021. PMID: 33510133 Free PMC article.
The immunology of HIV infection: implications for therapy.
Yarchoan R, Mitsuya H, Broder S. Yarchoan R, et al. Among authors: mitsuya h. AIDS Res Hum Retroviruses. 1992 Jun;8(6):1023-31. doi: 10.1089/aid.1992.8.1023. AIDS Res Hum Retroviruses. 1992. PMID: 1503817 Review.
NIH conference. Antiretroviral therapy in AIDS.
Broder S, Mitsuya H, Yarchoan R, Pavlakis GN. Broder S, et al. Among authors: mitsuya h. Ann Intern Med. 1990 Oct 15;113(8):604-18. doi: 10.7326/0003-4819-113-8-604. Ann Intern Med. 1990. PMID: 1698042 Review.
Immunologic issues in anti-retroviral therapy.
Yarchoan R, Mitsuya H, Broder S. Yarchoan R, et al. Among authors: mitsuya h. Immunol Today. 1990 Sep;11(9):327-33. doi: 10.1016/0167-5699(90)90128-v. Immunol Today. 1990. PMID: 1698379 Review.
Molecular targets for AIDS therapy.
Mitsuya H, Yarchoan R, Broder S. Mitsuya H, et al. Science. 1990 Sep 28;249(4976):1533-44. doi: 10.1126/science.1699273. Science. 1990. PMID: 1699273 Review.
Hematologic effects of AIDS therapies.
Pluda JM, Mitsuya H, Yarchoan R. Pluda JM, et al. Among authors: mitsuya h. Hematol Oncol Clin North Am. 1991 Apr;5(2):229-48. Hematol Oncol Clin North Am. 1991. PMID: 1708759 Review.
Strategies for the combination therapy of HIV infection.
Yarchoan R, Mitsuya H, Broder S. Yarchoan R, et al. Among authors: mitsuya h. J Acquir Immune Defic Syndr (1988). 1990;3 Suppl 2:S99-103. J Acquir Immune Defic Syndr (1988). 1990. PMID: 2172507 No abstract available.
709 results