Mitschke J - Search Results

1

The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer.

Krebs AM, Mitschke J, Lasierra Losada M, Schmalhofer O, Boerries M, Busch H, Boettcher M, Mougiakakos D, Reichardt W, Bronsert P, Brunton VG, Pilarsky C, Winkler TH, Brabletz S, Stemmler MP, Brabletz T. Krebs AM, et al. Among authors: mitschke j. Nat Cell Biol. 2017 May;19(5):518-529. doi: 10.1038/ncb3513. Epub 2017 Apr 17. Nat Cell Biol. 2017. PMID: 28414315

2

Generation and characterization of mice for conditional inactivation of Zeb1.

Brabletz S, Lasierra Losada M, Schmalhofer O, Mitschke J, Krebs A, Brabletz T, Stemmler MP. Brabletz S, et al. Among authors: mitschke j. Genesis. 2017 Apr;55(4). doi: 10.1002/dvg.23024. Epub 2017 Feb 23. Genesis. 2017. PMID: 28176446

3

Cathepsin D deficiency in mammary epithelium transiently stalls breast cancer by interference with mTORC1 signaling.

Ketterer S, Mitschke J, Ketscher A, Schlimpert M, Reichardt W, Baeuerle N, Hess ME, Metzger P, Boerries M, Peters C, Kammerer B, Brummer T, Steinberg F, Reinheckel T. Ketterer S, et al. Among authors: mitschke j. Nat Commun. 2020 Oct 12;11(1):5133. doi: 10.1038/s41467-020-18935-2. Nat Commun. 2020. PMID: 33046706 Free PMC article.

4

The role of proteases in epithelial-to-mesenchymal cell transitions in cancer.

Mitschke J, Burk UC, Reinheckel T. Mitschke J, et al. Cancer Metastasis Rev. 2019 Sep;38(3):431-444. doi: 10.1007/s10555-019-09808-2. Cancer Metastasis Rev. 2019. PMID: 31482486 Review.

5

Lysosomal damage drives mitochondrial proteome remodelling and reprograms macrophage immunometabolism.

Bussi C, Heunis T, Pellegrino E, Bernard EM, Bah N, Dos Santos MS, Santucci P, Aylan B, Rodgers A, Fearns A, Mitschke J, Moore C, MacRae JI, Greco M, Reinheckel T, Trost M, Gutierrez MG. Bussi C, et al. Among authors: mitschke j. Nat Commun. 2022 Nov 28;13(1):7338. doi: 10.1038/s41467-022-34632-8. Nat Commun. 2022. PMID: 36443305 Free PMC article.

6

Neuronal-specific microexon splicing of TAF1 mRNA is directly regulated by SRRM4/nSR100.

Capponi S, Stöffler N, Irimia M, Van Schaik FMA, Ondik MM, Biniossek ML, Lehmann L, Mitschke J, Vermunt MW, Creyghton MP, Graybiel AM, Reinheckel T, Schilling O, Blencowe BJ, Crittenden JR, Timmers HTM. Capponi S, et al. Among authors: mitschke j. RNA Biol. 2020 Jan;17(1):62-74. doi: 10.1080/15476286.2019.1667214. Epub 2019 Sep 27. RNA Biol. 2020. PMID: 31559909 Free PMC article.

7

Cathepsin D inhibition during neuronal differentiation selectively affects individual proteins instead of overall protein turnover.

Schneider J, Mitschke J, Bhat M, Vogele D, Schilling O, Reinheckel T, Heß L. Schneider J, et al. Among authors: mitschke j. Biochimie. 2024 Mar 28:S0300-9084(24)00071-3. doi: 10.1016/j.biochi.2024.03.013. Online ahead of print. Biochimie. 2024. PMID: 38552867 Free article.

8

Circulating Tumor DNA Profiling for Detection, Risk Stratification, and Classification of Brain Lymphomas.

Mutter JA, Alig SK, Esfahani MS, Lauer EM, Mitschke J, Kurtz DM, Kühn J, Bleul S, Olsen M, Liu CL, Jin MC, Macaulay CW, Neidert N, Volk T, Eisenblaetter M, Rauer S, Heiland DH, Finke J, Duyster J, Wehrle J, Prinz M, Illerhaus G, Reinacher PC, Schorb E, Diehn M, Alizadeh AA, Scherer F. Mutter JA, et al. Among authors: mitschke j. J Clin Oncol. 2023 Mar 20;41(9):1684-1694. doi: 10.1200/JCO.22.00826. Epub 2022 Dec 21. J Clin Oncol. 2023. PMID: 36542815 Free PMC article.

9

Degradome-focused RNA interference screens to identify proteases important for breast cancer cell growth.

Hölzen L, Syré K, Mitschke J, Brummer T, Miething C, Reinheckel T. Hölzen L, et al. Among authors: mitschke j. Front Oncol. 2022 Oct 12;12:960109. doi: 10.3389/fonc.2022.960109. eCollection 2022. Front Oncol. 2022. PMID: 36313646 Free PMC article.

10

RNA interference screens discover proteases as synthetic lethal partners of PI3K inhibition in breast cancer cells.

Hölzen L, Mitschke J, Schönichen C, Hess ME, Ehrenfeld S, Boerries M, Miething C, Brummer T, Reinheckel T. Hölzen L, et al. Among authors: mitschke j. Theranostics. 2022 May 16;12(9):4348-4373. doi: 10.7150/thno.68299. eCollection 2022. Theranostics. 2022. PMID: 35673573 Free PMC article.

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