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Page 1
Discoidin domain receptor 1 activation links extracellular matrix to podocyte lipotoxicity in Alport syndrome.
Kim JJ, David JM, Wilbon SS, Santos JV, Patel DM, Ahmad A, Mitrofanova A, Liu X, Mallela SK, Ducasa GM, Ge M, Sloan AJ, Al-Ali H, Boulina M, Mendez AJ, Contreras GN, Prunotto M, Sohail A, Fridman R, Miner JH, Merscher S, Fornoni A. Kim JJ, et al. Among authors: mitrofanova a. EBioMedicine. 2021 Jan;63:103162. doi: 10.1016/j.ebiom.2020.103162. Epub 2020 Dec 16. EBioMedicine. 2021. PMID: 33340991 Free PMC article.
Podocyte-specific GLUT4-deficient mice have fewer and larger podocytes and are protected from diabetic nephropathy.
Guzman J, Jauregui AN, Merscher-Gomez S, Maiguel D, Muresan C, Mitrofanova A, Diez-Sampedro A, Szust J, Yoo TH, Villarreal R, Pedigo C, Molano RD, Johnson K, Kahn B, Hartleben B, Huber TB, Saha J, Burke GW 3rd, Abel ED, Brosius FC, Fornoni A. Guzman J, et al. Among authors: mitrofanova a. Diabetes. 2014 Feb;63(2):701-14. doi: 10.2337/db13-0752. Epub 2013 Oct 7. Diabetes. 2014. PMID: 24101677 Free PMC article.
Sphingomyelinase-like phosphodiesterase 3b expression levels determine podocyte injury phenotypes in glomerular disease.
Yoo TH, Pedigo CE, Guzman J, Correa-Medina M, Wei C, Villarreal R, Mitrofanova A, Leclercq F, Faul C, Li J, Kretzler M, Nelson RG, Lehto M, Forsblom C, Groop PH, Reiser J, Burke GW, Fornoni A, Merscher S. Yoo TH, et al. Among authors: mitrofanova a. J Am Soc Nephrol. 2015 Jan;26(1):133-47. doi: 10.1681/ASN.2013111213. Epub 2014 Jun 12. J Am Soc Nephrol. 2015. PMID: 24925721 Free PMC article.
Nephrin Contributes to Insulin Secretion and Affects Mammalian Target of Rapamycin Signaling Independently of Insulin Receptor.
Villarreal R, Mitrofanova A, Maiguel D, Morales X, Jeon J, Grahammer F, Leibiger IB, Guzman J, Fachado A, Yoo TH, Busher Katin A, Gellermann J, Merscher S, Burke GW, Berggren PO, Oh J, Huber TB, Fornoni A. Villarreal R, et al. Among authors: mitrofanova a. J Am Soc Nephrol. 2016 Apr;27(4):1029-41. doi: 10.1681/ASN.2015020210. Epub 2015 Sep 23. J Am Soc Nephrol. 2016. PMID: 26400569 Free PMC article.
Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury.
Pedigo CE, Ducasa GM, Leclercq F, Sloan A, Mitrofanova A, Hashmi T, Molina-David J, Ge M, Lassenius MI, Forsblom C, Lehto M, Groop PH, Kretzler M, Eddy S, Martini S, Reich H, Wahl P, Ghiggeri G, Faul C, Burke GW 3rd, Kretz O, Huber TB, Mendez AJ, Merscher S, Fornoni A. Pedigo CE, et al. Among authors: mitrofanova a. J Clin Invest. 2016 Sep 1;126(9):3336-50. doi: 10.1172/JCI85939. Epub 2016 Aug 2. J Clin Invest. 2016. PMID: 27482889 Free PMC article.
Sphingomyelinase-like phosphodiesterase 3b mediates radiation-induced damage of renal podocytes.
Ahmad A, Mitrofanova A, Bielawski J, Yang Y, Marples B, Fornoni A, Zeidan YH. Ahmad A, et al. Among authors: mitrofanova a. FASEB J. 2017 Feb;31(2):771-780. doi: 10.1096/fj.201600618R. Epub 2016 Nov 11. FASEB J. 2017. PMID: 27836988 Free PMC article.
The lipid-modulating enzyme sphingomyelin phosphodiesterase acid-like 3B (SMPDL3b) is a key determinant of podocyte injury and a known off target of the anti-CD20 antibody rituximab (RTX). ...-Ahmad, A., Mitrofanova, A., Bielawski, J., Yang, Y., …
The lipid-modulating enzyme sphingomyelin phosphodiesterase acid-like 3B (SMPDL3b) is a key determinant of podocyte injury and a …
Hydroxypropyl-β-cyclodextrin protects from kidney disease in experimental Alport syndrome and focal segmental glomerulosclerosis.
Mitrofanova A, Molina J, Varona Santos J, Guzman J, Morales XA, Ducasa GM, Bryn J, Sloan A, Volosenco I, Kim JJ, Ge M, Mallela SK, Kretzler M, Eddy S, Martini S, Wahl P, Pastori S, Mendez AJ, Burke GW, Merscher S, Fornoni A. Mitrofanova A, et al. Kidney Int. 2018 Dec;94(6):1151-1159. doi: 10.1016/j.kint.2018.06.031. Epub 2018 Oct 6. Kidney Int. 2018. PMID: 30301568 Free PMC article.
SMPDL3b modulates insulin receptor signaling in diabetic kidney disease.
Mitrofanova A, Mallela SK, Ducasa GM, Yoo TH, Rosenfeld-Gur E, Zelnik ID, Molina J, Varona Santos J, Ge M, Sloan A, Kim JJ, Pedigo C, Bryn J, Volosenco I, Faul C, Zeidan YH, Garcia Hernandez C, Mendez AJ, Leibiger I, Burke GW, Futerman AH, Barisoni L, Ishimoto Y, Inagi R, Merscher S, Fornoni A. Mitrofanova A, et al. Nat Commun. 2019 Jun 19;10(1):2692. doi: 10.1038/s41467-019-10584-4. Nat Commun. 2019. PMID: 31217420 Free PMC article.
ATP-binding cassette A1 deficiency causes cardiolipin-driven mitochondrial dysfunction in podocytes.
Ducasa GM, Mitrofanova A, Mallela SK, Liu X, Molina J, Sloan A, Pedigo CE, Ge M, Santos JV, Hernandez Y, Kim JJ, Maugeais C, Mendez AJ, Nair V, Kretzler M, Burke GW, Nelson RG, Ishimoto Y, Inagi R, Banerjee S, Liu S, Szeto HH, Merscher S, Fontanesi F, Fornoni A. Ducasa GM, et al. Among authors: mitrofanova a. J Clin Invest. 2019 Jul 22;129(8):3387-3400. doi: 10.1172/JCI125316. eCollection 2019 Jul 22. J Clin Invest. 2019. PMID: 31329164 Free PMC article.
90 results