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Loss of CLN3, the gene mutated in juvenile neuronal ceroid lipofuscinosis, leads to metabolic impairment and autophagy induction in retinal pigment epithelium.
Zhong Y, Mohan K, Liu J, Al-Attar A, Lin P, Flight RM, Sun Q, Warmoes MO, Deshpande RR, Liu H, Jung KS, Mitov MI, Lin N, Butterfield DA, Lu S, Liu J, Moseley HNB, Fan TWM, Kleinman ME, Wang QJ. Zhong Y, et al. Among authors: mitov mi. Biochim Biophys Acta Mol Basis Dis. 2020 Oct 1;1866(10):165883. doi: 10.1016/j.bbadis.2020.165883. Epub 2020 Jun 25. Biochim Biophys Acta Mol Basis Dis. 2020. PMID: 32592935 Free PMC article.
Redox proteomic identification of HNE-bound mitochondrial proteins in cardiac tissues reveals a systemic effect on energy metabolism after doxorubicin treatment.
Zhao Y, Miriyala S, Miao L, Mitov M, Schnell D, Dhar SK, Cai J, Klein JB, Sultana R, Butterfield DA, Vore M, Batinic-Haberle I, Bondada S, St Clair DK. Zhao Y, et al. Free Radic Biol Med. 2014 Jul;72:55-65. doi: 10.1016/j.freeradbiomed.2014.03.001. Epub 2014 Mar 12. Free Radic Biol Med. 2014. PMID: 24632380 Free PMC article.
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