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Bacterial retrons encode phage-defending tripartite toxin-antitoxin systems.
Bobonis J, Mitosch K, Mateus A, Karcher N, Kritikos G, Selkrig J, Zietek M, Monzon V, Pfalz B, Garcia-Santamarina S, Galardini M, Sueki A, Kobayashi C, Stein F, Bateman A, Zeller G, Savitski MM, Elfenbein JR, Andrews-Polymenis HL, Typas A. Bobonis J, et al. Among authors: mitosch k. Nature. 2022 Sep;609(7925):144-150. doi: 10.1038/s41586-022-05091-4. Epub 2022 Jul 18. Nature. 2022. PMID: 35850148
The functional proteome landscape of Escherichia coli.
Mateus A, Hevler J, Bobonis J, Kurzawa N, Shah M, Mitosch K, Goemans CV, Helm D, Stein F, Typas A, Savitski MM. Mateus A, et al. Among authors: mitosch k. Nature. 2020 Dec;588(7838):473-478. doi: 10.1038/s41586-020-3002-5. Epub 2020 Dec 9. Nature. 2020. PMID: 33299184 Free PMC article.
SARS-CoV-2 infection remodels the host protein thermal stability landscape.
Selkrig J, Stanifer M, Mateus A, Mitosch K, Barrio-Hernandez I, Rettel M, Kim H, Voogdt CGP, Walch P, Kee C, Kurzawa N, Stein F, Potel C, Jarzab A, Kuster B, Bartenschlager R, Boulant S, Beltrao P, Typas A, Savitski MM. Selkrig J, et al. Among authors: mitosch k. Mol Syst Biol. 2021 Feb;17(2):e10188. doi: 10.15252/msb.202010188. Mol Syst Biol. 2021. PMID: 33590968 Free PMC article.
Systematic analysis of drug combinations against Gram-positive bacteria.
Cacace E, Kim V, Varik V, Knopp M, Tietgen M, Brauer-Nikonow A, Inecik K, Mateus A, Milanese A, Mårli MT, Mitosch K, Selkrig J, Brochado AR, Kuipers OP, Kjos M, Zeller G, Savitski MM, Göttig S, Huber W, Typas A. Cacace E, et al. Among authors: mitosch k. Nat Microbiol. 2023 Nov;8(11):2196-2212. doi: 10.1038/s41564-023-01486-9. Epub 2023 Sep 28. Nat Microbiol. 2023. PMID: 37770760 Free PMC article.