Mitchison TJ - Search Results

1

Tubulin Resists Degradation by Cereblon-Recruiting PROTACs.

Gasic I, Groendyke BJ, Nowak RP, Yuan JC, Kalabathula J, Fischer ES, Gray NS, Mitchison TJ. Gasic I, et al. Among authors: mitchison tj. Cells. 2020 Apr 27;9(5):1083. doi: 10.3390/cells9051083. Cells. 2020. PMID: 32349222 Free PMC article.

2

Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL.

Degterev A, Lugovskoy A, Cardone M, Mulley B, Wagner G, Mitchison T, Yuan J. Degterev A, et al. Nat Cell Biol. 2001 Feb;3(2):173-82. doi: 10.1038/35055085. Nat Cell Biol. 2001. PMID: 11175750

3

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury.

Degterev A, Huang Z, Boyce M, Li Y, Jagtap P, Mizushima N, Cuny GD, Mitchison TJ, Moskowitz MA, Yuan J. Degterev A, et al. Among authors: mitchison tj. Nat Chem Biol. 2005 Jul;1(2):112-9. doi: 10.1038/nchembio711. Epub 2005 May 29. Nat Chem Biol. 2005. PMID: 16408008

4

Caspase-11 regulates cell migration by promoting Aip1-Cofilin-mediated actin depolymerization.

Li J, Brieher WM, Scimone ML, Kang SJ, Zhu H, Yin H, von Andrian UH, Mitchison T, Yuan J. Li J, et al. Nat Cell Biol. 2007 Mar;9(3):276-86. doi: 10.1038/ncb1541. Epub 2007 Feb 11. Nat Cell Biol. 2007. PMID: 17293856

5

Selective aurora kinase inhibitors identified using a taxol-induced checkpoint sensitivity screen.

Kwiatkowski N, Deng X, Wang J, Tan L, Villa F, Santaguida S, Huang HC, Mitchison T, Musacchio A, Gray N. Kwiatkowski N, et al. ACS Chem Biol. 2012 Jan 20;7(1):185-96. doi: 10.1021/cb200305u. Epub 2011 Oct 21. ACS Chem Biol. 2012. PMID: 21992004 Free PMC article.

6

MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells.

Wang Y, Lee YM, Baitsch L, Huang A, Xiang Y, Tong H, Lako A, Von T, Choi C, Lim E, Min J, Li L, Stegmeier F, Schlegel R, Eck MJ, Gray NS, Mitchison TJ, Zhao JJ. Wang Y, et al. Among authors: mitchison tj. Elife. 2014 May 20;3:e01763. doi: 10.7554/eLife.01763. Elife. 2014. PMID: 24844244 Free PMC article.

7

Mitotic MELK-eIF4B signaling controls protein synthesis and tumor cell survival.

Wang Y, Begley M, Li Q, Huang HT, Lako A, Eck MJ, Gray NS, Mitchison TJ, Cantley LC, Zhao JJ. Wang Y, et al. Among authors: mitchison tj. Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):9810-5. doi: 10.1073/pnas.1606862113. Epub 2016 Aug 15. Proc Natl Acad Sci U S A. 2016. PMID: 27528663 Free PMC article.

8

Autoregulation and repair in microtubule homeostasis.

Gasic I, Mitchison TJ. Gasic I, et al. Among authors: mitchison tj. Curr Opin Cell Biol. 2019 Feb;56:80-87. doi: 10.1016/j.ceb.2018.10.003. Epub 2018 Nov 8. Curr Opin Cell Biol. 2019. PMID: 30415186 Review.

9

Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models.

Silva MC, Ferguson FM, Cai Q, Donovan KA, Nandi G, Patnaik D, Zhang T, Huang HT, Lucente DE, Dickerson BC, Mitchison TJ, Fischer ES, Gray NS, Haggarty SJ. Silva MC, et al. Among authors: mitchison tj. Elife. 2019 Mar 25;8:e45457. doi: 10.7554/eLife.45457. Elife. 2019. PMID: 30907729 Free PMC article.

10

Tubulin mRNA stability is sensitive to change in microtubule dynamics caused by multiple physiological and toxic cues.

Gasic I, Boswell SA, Mitchison TJ. Gasic I, et al. Among authors: mitchison tj. PLoS Biol. 2019 Apr 9;17(4):e3000225. doi: 10.1371/journal.pbio.3000225. eCollection 2019 Apr. PLoS Biol. 2019. PMID: 30964857 Free PMC article.

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