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Doxorubicin-conjugated siRNA lipid nanoparticles for combination cancer therapy.
Butowska K, Han X, Gong N, El-Mayta R, Haley RM, Xue L, Zhong W, Guo W, Wang K, Mitchell MJ. Butowska K, et al. Among authors: mitchell mj. Acta Pharm Sin B. 2023 Apr;13(4):1429-1437. doi: 10.1016/j.apsb.2022.07.011. Epub 2022 Jul 21. Acta Pharm Sin B. 2023. PMID: 37139433 Free PMC article.
Oral formulation of Wnt inhibitor complex reduces inflammation and fibrosis in intraperitoneal implants in vivo.
de Castro Santos AL, da Silva NJA, Viana CTR, Dos Santos LCC, da Silva GHC, Scalzo Júnior SRA, Costa PAC, da Silva WN, de Jesus ICG, Birbrair A, de Magalhães MTQ, Frézard F, Guatimosim S, Haley RM, Mitchell MJ, Andrade SP, Campos PP, Guimaraes PPG. de Castro Santos AL, et al. Among authors: mitchell mj. Drug Deliv Transl Res. 2023 May;13(5):1420-1435. doi: 10.1007/s13346-023-01303-0. Epub 2023 Feb 7. Drug Deliv Transl Res. 2023. PMID: 36749480
Upregulation of exosome secretion from tumor-associated macrophages plays a key role in the suppression of anti-tumor immunity.
Zhong W, Lu Y, Han X, Yang J, Qin Z, Zhang W, Yu Z, Wu B, Liu S, Xu W, Zheng C, Schuchter LM, Karakousis GC, Mitchell TC, Amaravadi R, Flowers AJ, Gimotty PA, Xiao M, Mills G, Herlyn M, Dong H, Mitchell MJ, Kim J, Xu X, Guo W. Zhong W, et al. Among authors: mitchell tc, mitchell mj. Cell Rep. 2023 Oct 31;42(10):113224. doi: 10.1016/j.celrep.2023.113224. Epub 2023 Oct 8. Cell Rep. 2023. PMID: 37805922 Free PMC article.
Bile acid-containing lipid nanoparticles enhance extrahepatic mRNA delivery.
Patel SK, Billingsley MM, Mukalel AJ, Thatte AS, Hamilton AG, Gong N, El-Mayta R, Safford HC, Merolle M, Mitchell MJ. Patel SK, et al. Among authors: mitchell mj. Theranostics. 2024 Jan 1;14(1):1-16. doi: 10.7150/thno.89913. eCollection 2024. Theranostics. 2024. PMID: 38164140 Free PMC article.
Delivery of Plasmid DNA by Ionizable Lipid Nanoparticles to Induce CAR Expression in T Cells.
Prazeres PHDM, Ferreira H, Costa PAC, da Silva W, Alves MT, Padilla M, Thatte A, Santos AK, Lobo AO, Sabino A, Del Puerto HL, Mitchell MJ, Guimaraes PPG. Prazeres PHDM, et al. Among authors: mitchell mj. Int J Nanomedicine. 2023 Oct 18;18:5891-5904. doi: 10.2147/IJN.S424723. eCollection 2023. Int J Nanomedicine. 2023. PMID: 37873551 Free PMC article.
siRNA lipid nanoparticles for CXCL12 silencing modulate brain immune response during Zika infection.
Costa PAC, da Silva WN, Moura Prazeres PHD, Ferreira HAS, da Silva NJA, Figueiredo MM, da Silva Oliveira B, Scalzo Júnior SRA, Silva Santos FRD, Fernandes RA, Palanki R, Hamilton AG, Birbrair A, Santos VR, de Miranda AS, Mitchell MJ, Teixeira MM, Costa VV, Guimarães PPG. Costa PAC, et al. Among authors: mitchell mj. Biomed Pharmacother. 2024 Jan;170:115981. doi: 10.1016/j.biopha.2023.115981. Epub 2023 Dec 12. Biomed Pharmacother. 2024. PMID: 38091634 Free article.
Emerging strategies for nanomedicine in autoimmunity.
Thatte AS, Billingsley MM, Weissman D, Melamed JR, Mitchell MJ. Thatte AS, et al. Among authors: mitchell mj. Adv Drug Deliv Rev. 2024 Apr;207:115194. doi: 10.1016/j.addr.2024.115194. Epub 2024 Feb 10. Adv Drug Deliv Rev. 2024. PMID: 38342243 Review.
Ionizable Lipid Nanoparticle-Mediated TRAIL mRNA Delivery in the Tumor Microenvironment to Inhibit Colon Cancer Progression.
da Silva WN, Carvalho Costa PA, Scalzo Júnior SRA, Ferreira HAS, Prazeres PHDM, Campos CLV, Rodrigues Alves MT, Alves da Silva NJ, de Castro Santos AL, Guimarães LC, Chen Ferris ME, Thatte A, Hamilton A, Bicalho KA, Lobo AO, Santiago HDC, da Silva Barcelos L, Figueiredo MM, Teixeira MM, Vasconcelos Costa V, Mitchell MJ, Frézard F, Pires Goulart Guimaraes P. da Silva WN, et al. Among authors: mitchell mj. Int J Nanomedicine. 2024 Mar 14;19:2655-2673. doi: 10.2147/IJN.S452896. eCollection 2024. Int J Nanomedicine. 2024. PMID: 38500680 Free PMC article.
350 results