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Rare variant associations with plasma protein levels in the UK Biobank.
Dhindsa RS, Burren OS, Sun BB, Prins BP, Matelska D, Wheeler E, Mitchell J, Oerton E, Hristova VA, Smith KR, Carss K, Wasilewski S, Harper AR, Paul DS, Fabre MA, Runz H, Viollet C, Challis B, Platt A; AstraZeneca Genomics Initiative; Vitsios D, Ashley EA, Whelan CD, Pangalos MN, Wang Q, Petrovski S. Dhindsa RS, et al. Among authors: mitchell j. Nature. 2023 Oct;622(7982):339-347. doi: 10.1038/s41586-023-06547-x. Epub 2023 Oct 4. Nature. 2023. PMID: 37794183 Free PMC article.
Human genetics uncovers MAP3K15 as an obesity-independent therapeutic target for diabetes.
Nag A, Dhindsa RS, Mitchell J, Vasavda C, Harper AR, Vitsios D, Ahnmark A, Bilican B, Madeyski-Bengtson K, Zarrouki B, Zoghbi AW, Wang Q, Smith KR, Alegre-Díaz J, Kuri-Morales P, Berumen J, Tapia-Conyer R, Emberson J, Torres JM, Collins R, Smith DM, Challis B, Paul DS, Bohlooly-Y M, Snowden M, Baker D, Fritsche-Danielson R, Pangalos MN, Petrovski S. Nag A, et al. Among authors: mitchell j. Sci Adv. 2022 Nov 18;8(46):eadd5430. doi: 10.1126/sciadv.add5430. Epub 2022 Nov 16. Sci Adv. 2022. PMID: 36383675 Free PMC article.
Clinical validation of C12FDG as a marker associated with senescence and osteoarthritic phenotypes.
Hambright WS, Duke VR, Goff AD, Goff AW, Minas LT, Kloser H, Gao X, Huard C, Guo P, Lu A, Mitchell J, Mullen M, Su C, Tchkonia T, Espindola Netto JM, Robbins PD, Niedernhofer LJ, Kirkland JL, Bahney CS, Philippon M, Huard J. Hambright WS, et al. Among authors: mitchell j. Aging Cell. 2024 May 6:e14113. doi: 10.1111/acel.14113. Online ahead of print. Aging Cell. 2024. PMID: 38708778
Neuronal innervation regulates the secretion of neurotrophic myokines and exosomes from skeletal muscle.
Huang KY, Upadhyay G, Ahn Y, Sakakura M, Pagan-Diaz GJ, Cho Y, Weiss AC, Huang C, Mitchell JW, Li J, Tan Y, Deng YH, Ellis-Mohr A, Dou Z, Zhang X, Kang S, Chen Q, Sweedler JV, Im SG, Bashir R, Chung HJ, Popescu G, Gillette MU, Gazzola M, Kong H. Huang KY, et al. Among authors: mitchell jw. Proc Natl Acad Sci U S A. 2024 May 7;121(19):e2313590121. doi: 10.1073/pnas.2313590121. Epub 2024 Apr 29. Proc Natl Acad Sci U S A. 2024. PMID: 38683978
8,347 results