Mitchell DC - Search Results

1

Proteome-wide mapping of short-lived proteins in human cells.

Li J, Cai Z, Vaites LP, Shen N, Mitchell DC, Huttlin EL, Paulo JA, Harry BL, Gygi SP. Li J, et al. Among authors: mitchell dc. Mol Cell. 2021 Nov 18;81(22):4722-4735.e5. doi: 10.1016/j.molcel.2021.09.015. Epub 2021 Oct 8. Mol Cell. 2021. PMID: 34626566 Free PMC article.

2

The Arg/N-degron pathway targets transcription factors and regulates specific genes.

Vu TTM, Mitchell DC, Gygi SP, Varshavsky A. Vu TTM, et al. Among authors: mitchell dc. Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31094-31104. doi: 10.1073/pnas.2020124117. Epub 2020 Nov 23. Proc Natl Acad Sci U S A. 2020. PMID: 33229537 Free PMC article.

3

Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries.

Kuljanin M, Mitchell DC, Schweppe DK, Gikandi AS, Nusinow DP, Bulloch NJ, Vinogradova EV, Wilson DL, Kool ET, Mancias JD, Cravatt BF, Gygi SP. Kuljanin M, et al. Among authors: mitchell dc. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4. Nat Biotechnol. 2021. PMID: 33398154 Free PMC article.

4

Assessing target engagement using proteome-wide solvent shift assays.

Van Vranken JG, Li J, Mitchell DC, Navarrete-Perea J, Gygi SP. Van Vranken JG, et al. Among authors: mitchell dc. Elife. 2021 Dec 8;10:e70784. doi: 10.7554/eLife.70784. Elife. 2021. PMID: 34878405 Free PMC article.

5

A proteome-wide atlas of drug mechanism of action.

Mitchell DC, Kuljanin M, Li J, Van Vranken JG, Bulloch N, Schweppe DK, Huttlin EL, Gygi SP. Mitchell DC, et al. Nat Biotechnol. 2023 Jun;41(6):845-857. doi: 10.1038/s41587-022-01539-0. Epub 2023 Jan 2. Nat Biotechnol. 2023. PMID: 36593396 Free PMC article.

6

The RNA-binding protein SART3 promotes miR-34a biogenesis and G₁ cell cycle arrest in lung cancer cells.

Sherman EJ, Mitchell DC, Garner AL. Sherman EJ, et al. Among authors: mitchell dc. J Biol Chem. 2019 Nov 15;294(46):17188-17196. doi: 10.1074/jbc.AC119.010419. Epub 2019 Oct 16. J Biol Chem. 2019. PMID: 31619517 Free PMC article.

7

Chemoproteomic Profiling Uncovers CDK4-Mediated Phosphorylation of the Translational Suppressor 4E-BP1.

Mitchell DC, Menon A, Garner AL. Mitchell DC, et al. Cell Chem Biol. 2019 Jul 18;26(7):980-990.e8. doi: 10.1016/j.chembiol.2019.03.012. Epub 2019 May 2. Cell Chem Biol. 2019. PMID: 31056462 Free PMC article.

8

High-Throughput Chemical Probing of Full-Length Protein-Protein Interactions.

Song JM, Menon A, Mitchell DC, Johnson OT, Garner AL. Song JM, et al. Among authors: mitchell dc. ACS Comb Sci. 2017 Dec 11;19(12):763-769. doi: 10.1021/acscombsci.7b00128. Epub 2017 Nov 14. ACS Comb Sci. 2017. PMID: 29112379 Free PMC article.

9

Synthetic Knockout Protein Standard for Evaluating Interference in Tandem Mass Tag-Based Proteomics.

Navarrete-Perea J, Li J, Mitchell DC, Chi A. Navarrete-Perea J, et al. Among authors: mitchell dc. Anal Chem. 2024 Apr 30;96(17):6836-6846. doi: 10.1021/acs.analchem.4c00871. Epub 2024 Apr 19. Anal Chem. 2024. PMID: 38640495

10

Highly specific intracellular ubiquitination of a small molecule.

Li W, Garcia-Rivera EM, Mitchell DC, Chick JM, Maetani M, Knapp JM, Matthews GM, Shirasaki R, de Matos Simoes R, Viswanathan V, Pulice JL, Rees MG, Roth JA, Gygi SP, Mitsiades CS, Kadoch C, Schreiber SL, Ostrem JML. Li W, et al. Among authors: mitchell dc. bioRxiv [Preprint]. 2024 Jan 28:2024.01.26.577493. doi: 10.1101/2024.01.26.577493. bioRxiv. 2024. PMID: 38328167 Free PMC article. Preprint.

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