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Page 1
Chemokine receptor antagonist development.
Garin A, Johnson Z, Hermant A, Beltran F, Ratinaud Y, Michel A, Krohn S, Gaudet M, Carboni S, Ji H, Missotten M, Leger O, Power C, Proudfoot A. Garin A, et al. Among authors: missotten m. Methods Mol Biol. 2013;1013:67-92. doi: 10.1007/978-1-62703-426-5_6. Methods Mol Biol. 2013. PMID: 23625494
Discovery of a novel series of CXCR3 antagonists.
Crosignani S, Missotten M, Cleva C, Dondi R, Ratinaud Y, Humbert Y, Mandal AB, Bombrun A, Power C, Chollet A, Proudfoot A. Crosignani S, et al. Among authors: missotten m. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3614-7. doi: 10.1016/j.bmcl.2010.04.113. Epub 2010 Apr 28. Bioorg Med Chem Lett. 2010. PMID: 20483605
Discovery of potent, selective, and orally bioavailable alkynylphenoxyacetic acid CRTH2 (DP2) receptor antagonists for the treatment of allergic inflammatory diseases.
Crosignani S, Prêtre A, Jorand-Lebrun C, Fraboulet G, Seenisamy J, Augustine JK, Missotten M, Humbert Y, Cleva C, Abla N, Daff H, Schott O, Schneider M, Burgat-Charvillon F, Rivron D, Hamernig I, Arrighi JF, Gaudet M, Zimmerli SC, Juillard P, Johnson Z. Crosignani S, et al. Among authors: missotten m. J Med Chem. 2011 Oct 27;54(20):7299-317. doi: 10.1021/jm200866y. Epub 2011 Oct 3. J Med Chem. 2011. PMID: 21916510
Discovery of a new class of potent, selective, and orally bioavailable CRTH2 (DP2) receptor antagonists for the treatment of allergic inflammatory diseases.
Crosignani S, Page P, Missotten M, Colovray V, Cleva C, Arrighi JF, Atherall J, Macritchie J, Martin T, Humbert Y, Gaudet M, Pupowicz D, Maio M, Pittet PA, Golzio L, Giachetti C, Rocha C, Bernardinelli G, Filinchuk Y, Scheer A, Schwarz MK, Chollet A. Crosignani S, et al. Among authors: missotten m. J Med Chem. 2008 Apr 10;51(7):2227-43. doi: 10.1021/jm701383e. Epub 2008 Mar 5. J Med Chem. 2008. PMID: 18318469
Discovery of a Novel Series of CRTH2 (DP2) Receptor Antagonists Devoid of Carboxylic Acids.
Crosignani S, Jorand-Lebrun C, Campbell G, Prêtre A, Grippi-Vallotton T, Quattropani A, Bouscary-Desforges G, Bombrun A, Missotten M, Humbert Y, Frémaux C, Pâquet M, El Harkani K, Bradshaw CG, Cleva C, Abla N, Daff H, Schott O, Pittet PA, Arrighi JF, Gaudet M, Johnson Z. Crosignani S, et al. Among authors: missotten m. ACS Med Chem Lett. 2011 Oct 10;2(12):938-42. doi: 10.1021/ml200223s. eCollection 2011 Dec 8. ACS Med Chem Lett. 2011. PMID: 24900284 Free PMC article.
Discovery and development of a new class of potent, selective, orally active oxytocin receptor antagonists.
Quattropani A, Dorbais J, Covini D, Pittet PA, Colovray V, Thomas RJ, Coxhead R, Halazy S, Scheer A, Missotten M, Ayala G, Bradshaw C, De Raemy-Schenk AM, Nichols A, Cirillo R, Tos EG, Giachetti C, Golzio L, Marinelli P, Church DJ, Barberis C, Chollet A, Schwarz MK. Quattropani A, et al. Among authors: missotten m. J Med Chem. 2005 Dec 1;48(24):7882-905. doi: 10.1021/jm050645f. J Med Chem. 2005. PMID: 16302826
The DRY motif as a molecular switch of the human oxytocin receptor.
Favre N, Fanelli F, Missotten M, Nichols A, Wilson J, di Tiani M, Rommel C, Scheer A. Favre N, et al. Among authors: missotten m. Biochemistry. 2005 Aug 2;44(30):9990-10008. doi: 10.1021/bi0509853. Biochemistry. 2005. PMID: 16042376
25 results