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A new, easily generated mouse model of diabetic kidney fibrosis.
He X, Zhang T, Tolosa M, Goru SK, Chen X, Misra PS, Robinson LA, Yuen DA. He X, et al. Among authors: misra ps. Sci Rep. 2019 Aug 29;9(1):12549. doi: 10.1038/s41598-019-49012-4. Sci Rep. 2019. PMID: 31467329 Free PMC article.
Overexpression of the Severe Acute Respiratory Syndrome Coronavirus-2 Receptor, Angiotensin-Converting Enzyme 2, in Diabetic Kidney Disease: Implications for Kidney Injury in Novel Coronavirus Disease 2019.
Gilbert RE, Caldwell L, Misra PS, Chan K, Burns KD, Wrana JL, Yuen DA. Gilbert RE, et al. Among authors: misra ps. Can J Diabetes. 2021 Mar;45(2):162-166.e1. doi: 10.1016/j.jcjd.2020.07.003. Epub 2020 Jul 18. Can J Diabetes. 2021. PMID: 32917504 Free PMC article.
Myofibroblast YAP/TAZ activation is a key step in organ fibrogenesis.
He X, Tolosa MF, Zhang T, Goru SK, Ulloa Severino L, Misra PS, McEvoy CM, Caldwell L, Szeto SG, Gao F, Chen X, Atin C, Ki V, Vukosa N, Hu C, Zhang J, Yip C, Krizova A, Wrana JL, Yuen DA. He X, et al. Among authors: misra ps. JCI Insight. 2022 Feb 22;7(4):e146243. doi: 10.1172/jci.insight.146243. JCI Insight. 2022. PMID: 35191398 Free PMC article.
NUAK1 promotes organ fibrosis via YAP and TGF-β/SMAD signaling.
Zhang T, He X, Caldwell L, Goru SK, Ulloa Severino L, Tolosa MF, Misra PS, McEvoy CM, Christova T, Liu Y, Atin C, Zhang J, Hu C, Vukosa N, Chen X, Krizova A, Kirpalani A, Gregorieff A, Ni R, Chan K, Gill MK, Attisano L, Wrana JL, Yuen DA. Zhang T, et al. Among authors: misra ps. Sci Transl Med. 2022 Mar 23;14(637):eaaz4028. doi: 10.1126/scitranslmed.aaz4028. Epub 2022 Mar 23. Sci Transl Med. 2022. PMID: 35320001
Dual Role of Caspase 8 in Adipocyte Apoptosis and Metabolic Inflammation.
Luk CT, Chan CK, Chiu F, Shi SY, Misra PS, Li YZ, Pollock-Tahiri E, Schroer SA, Desai HR, Sivasubramaniyam T, Cai EP, Krishnamurthy M, Han DJ, Chowdhury A, Aslam R, Yuen DA, Hakem A, Hakem R, Woo M. Luk CT, et al. Among authors: misra ps. Diabetes. 2023 Dec 1;72(12):1751-1765. doi: 10.2337/db22-1033. Diabetes. 2023. PMID: 37699387
29 results