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Population-level variation in enhancer expression identifies disease mechanisms in the human brain.
Dong P, Hoffman GE, Apontes P, Bendl J, Rahman S, Fernando MB, Zeng B, Vicari JM, Zhang W, Girdhar K, Townsley KG, Misir R; CommonMind Consortium; Brennand KJ, Haroutunian V, Voloudakis G, Fullard JF, Roussos P. Dong P, et al. Among authors: misir r. Nat Genet. 2022 Oct;54(10):1493-1503. doi: 10.1038/s41588-022-01170-4. Epub 2022 Sep 26. Nat Genet. 2022. PMID: 36163279 Free PMC article.
Differential activity of transcribed enhancers in the prefrontal cortex of 537 cases with schizophrenia and controls.
Hauberg ME, Fullard JF, Zhu L, Cohain AT, Giambartolomei C, Misir R, Reach S, Johnson JS, Wang M, Mattheisen M, Børglum AD, Zhang B, Sieberts SK, Peters MA, Domenici E, Schadt EE, Devlin B, Sklar P, Roeder K, Roussos P; CommonMind Consortium. Hauberg ME, et al. Among authors: misir r. Mol Psychiatry. 2019 Nov;24(11):1685-1695. doi: 10.1038/s41380-018-0059-8. Epub 2018 May 8. Mol Psychiatry. 2019. PMID: 29740122 Free PMC article.
The three-dimensional landscape of cortical chromatin accessibility in Alzheimer's disease.
Bendl J, Hauberg ME, Girdhar K, Im E, Vicari JM, Rahman S, Fernando MB, Townsley KG, Dong P, Misir R, Kleopoulos SP, Reach SM, Apontes P, Zeng B, Zhang W, Voloudakis G, Brennand KJ, Nixon RA, Haroutunian V, Hoffman GE, Fullard JF, Roussos P. Bendl J, et al. Among authors: misir r. Nat Neurosci. 2022 Oct;25(10):1366-1378. doi: 10.1038/s41593-022-01166-7. Epub 2022 Sep 28. Nat Neurosci. 2022. PMID: 36171428 Free PMC article.
Lineage specific 3D genome structure in the adult human brain and neurodevelopmental changes in the chromatin interactome.
Rahman S, Dong P, Apontes P, Fernando MB, Kosoy R, Townsley KG, Girdhar K, Bendl J, Shao Z, Misir R, Tsankova N, Kleopoulos SP, Brennand KJ, Fullard JF, Roussos P. Rahman S, et al. Among authors: misir r. Nucleic Acids Res. 2023 Nov 10;51(20):11142-11161. doi: 10.1093/nar/gkad798. Nucleic Acids Res. 2023. PMID: 37811875 Free PMC article.
The neuronal chromatin landscape in adult schizophrenia brains is linked to early fetal development.
Girdhar K, Bendl J, Baumgartner A, Therrien K, Venkatesh S, Mathur D, Dong P, Rahman S, Kleopoulos SP, Misir R, Reach SM, Auluck PK, Marenco S, Lewis DA, Haroutunian V, Funk C, Voloudakis G, Hoffman GE, Fullard JF, Roussos P. Girdhar K, et al. Among authors: misir r. Res Sq [Preprint]. 2023 Oct 2:rs.3.rs-3393581. doi: 10.21203/rs.3.rs-3393581/v1. Res Sq. 2023. PMID: 37886514 Free PMC article. Preprint.
The neuronal chromatin landscape in adult schizophrenia brains is linked to early fetal development.
Girdhar K, Bendl J, Baumgartner A, Therrien K, Venkatesh S, Mathur D, Dong P, Rahman S, Kleopoulos SP, Misir R, Reach SM, Auluck PK, Marenco S, Lewis DA, Haroutunian V, Funk C, Voloudakis G, Hoffman GE, Fullard JF, Roussos P. Girdhar K, et al. Among authors: misir r. medRxiv [Preprint]. 2023 Oct 3:2023.10.02.23296067. doi: 10.1101/2023.10.02.23296067. medRxiv. 2023. PMID: 37873320 Free PMC article. Preprint.
18 results