Mirams GR - Search Results

1

Empirical Quantification of Predictive Uncertainty Due to Model Discrepancy by Training with an Ensemble of Experimental Designs: An Application to Ion Channel Kinetics.

Shuttleworth JG, Lei CL, Whittaker DG, Windley MJ, Hill AP, Preston SP, Mirams GR. Shuttleworth JG, et al. Among authors: mirams gr. Bull Math Biol. 2023 Nov 24;86(1):2. doi: 10.1007/s11538-023-01224-6. Bull Math Biol. 2023. PMID: 37999811 Free PMC article.

2

Neural network emulation of the human ventricular cardiomyocyte action potential: a tool for more efficient computation in pharmacological studies.

Grandits T, Augustin CM, Haase G, Jost N, Mirams GR, Niederer SA, Plank G, Varró A, Virág L, Jung A. Grandits T, et al. Among authors: mirams gr. bioRxiv [Preprint]. 2023 Dec 25:2023.08.16.553497. doi: 10.1101/2023.08.16.553497. bioRxiv. 2023. PMID: 38234850 Free PMC article. Updated. Preprint.

3

A hybrid approach to multi-scale modelling of cancer.

Osborne JM, Walter A, Kershaw SK, Mirams GR, Fletcher AG, Pathmanathan P, Gavaghan D, Jensen OE, Maini PK, Byrne HM. Osborne JM, et al. Among authors: mirams gr. Philos Trans A Math Phys Eng Sci. 2010 Nov 13;368(1930):5013-28. doi: 10.1098/rsta.2010.0173. Philos Trans A Math Phys Eng Sci. 2010. PMID: 20921009

4

High resolution structural evidence suggests the Sarcoplasmic Reticulum forms microdomains with Acidic Stores (lysosomes) in the heart.

Aston D, Capel RA, Ford KL, Christian HC, Mirams GR, Rog-Zielinska EA, Kohl P, Galione A, Burton RA, Terrar DA. Aston D, et al. Among authors: mirams gr. Sci Rep. 2017 Jan 17;7:40620. doi: 10.1038/srep40620. Sci Rep. 2017. PMID: 28094777 Free PMC article.

5

Connexin43 contributes to electrotonic conduction across scar tissue in the intact heart.

Mahoney VM, Mezzano V, Mirams GR, Maass K, Li Z, Cerrone M, Vasquez C, Bapat A, Delmar M, Morley GE. Mahoney VM, et al. Among authors: mirams gr. Sci Rep. 2016 May 31;6:26744. doi: 10.1038/srep26744. Sci Rep. 2016. PMID: 27244564 Free PMC article.

6

Control of NFAT Isoform Activation and NFAT-Dependent Gene Expression through Two Coincident and Spatially Segregated Intracellular Ca²⁺ Signals.

Kar P, Mirams GR, Christian HC, Parekh AB. Kar P, et al. Among authors: mirams gr. Mol Cell. 2016 Nov 17;64(4):746-759. doi: 10.1016/j.molcel.2016.11.011. Mol Cell. 2016. PMID: 27863227 Free PMC article.

7

mRNA expression levels in failing human hearts predict cellular electrophysiological remodeling: a population-based simulation study.

Walmsley J, Rodriguez JF, Mirams GR, Burrage K, Efimov IR, Rodriguez B. Walmsley J, et al. Among authors: mirams gr. PLoS One. 2013;8(2):e56359. doi: 10.1371/journal.pone.0056359. Epub 2013 Feb 20. PLoS One. 2013. PMID: 23437117 Free PMC article.

8

Phenomenological modeling of cell-to-cell and beat-to-beat variability in isolated Guinea Pig ventricular myocytes.

Walmsley J, Mirams G, Bahoshy M, Bollensdorff C, Rodriguez B, Burrage K. Walmsley J, et al. Annu Int Conf IEEE Eng Med Biol Soc. 2010;2010:1457-60. doi: 10.1109/IEMBS.2010.5626858. Annu Int Conf IEEE Eng Med Biol Soc. 2010. PMID: 21096356

9

Modelling spatially regulated beta-catenin dynamics and invasion in intestinal crypts.

Murray PJ, Kang JW, Mirams GR, Shin SY, Byrne HM, Maini PK, Cho KH. Murray PJ, et al. Among authors: mirams gr. Biophys J. 2010 Aug 4;99(3):716-25. doi: 10.1016/j.bpj.2010.05.016. Biophys J. 2010. PMID: 20682248 Free PMC article.

10

Novel approaches to assessing cardiac safety--proceedings of a workshop: regulators, industry and academia discuss the future of in silico cardiac modelling to predict the proarrhythmic safety of drugs.

Fletcher K, Shah RR, Thomas A, Tobin F, Rodriguez B, Mirams GR, Saiz J, Noble D. Fletcher K, et al. Among authors: mirams gr. Drug Saf. 2011 May 1;34(5):439-43. doi: 10.2165/11591950-000000000-00000. Drug Saf. 2011. PMID: 21513366 Free PMC article. No abstract available.

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