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Anti-α-synuclein ASO delivered to monoamine neurons prevents α-synuclein accumulation in a Parkinson's disease-like mouse model and in monkeys.
Alarcón-Arís D, Pavia-Collado R, Miquel-Rio L, Coppola-Segovia V, Ferrés-Coy A, Ruiz-Bronchal E, Galofré M, Paz V, Campa L, Revilla R, Montefeltro A, Kordower JH, Vila M, Artigas F, Bortolozzi A. Alarcón-Arís D, et al. EBioMedicine. 2020 Sep;59:102944. doi: 10.1016/j.ebiom.2020.102944. Epub 2020 Aug 15. EBioMedicine. 2020. PMID: 32810825 Free PMC article.
Intracerebral Administration of a Ligand-ASO Conjugate Selectively Reduces α-Synuclein Accumulation in Monoamine Neurons of Double Mutant Human A30P*A53T*α-Synuclein Transgenic Mice.
Pavia-Collado R, Cóppola-Segovia V, Miquel-Rio L, Alarcón-Aris D, Rodríguez-Aller R, Torres-López M, Paz V, Ruiz-Bronchal E, Campa L, Artigas F, Montefeltro A, Revilla R, Bortolozzi A. Pavia-Collado R, et al. Int J Mol Sci. 2021 Mar 13;22(6):2939. doi: 10.3390/ijms22062939. Int J Mol Sci. 2021. PMID: 33805843 Free PMC article.
Corrigendum to "Anti-α-synuclein ASO delivered to monoamine neurons prevents α-synuclein accumulation in a Parkinson's disease-like mouse model and in monkeys" [EBioMedicine 2020; 59:102944].
Alarcón-Arís D, Pavia-Collado R, Miquel-Rio L, Coppola-Segovia V, Ferrés-Coy A, Ruiz-Bronchal E, Galofré M, Paz V, Campa L, Revilla R, Montefeltro A, Kordower JH, Vila M, Artigas F, Bortolozzi A. Alarcón-Arís D, et al. EBioMedicine. 2021 Dec;74:103731. doi: 10.1016/j.ebiom.2021.103731. Epub 2021 Nov 29. EBioMedicine. 2021. PMID: 34852293 Free PMC article. No abstract available.
Up and Down γ-Synuclein Transcription in Dopamine Neurons Translates into Changes in Dopamine Neurotransmission and Behavioral Performance in Mice.
Pavia-Collado R, Rodríguez-Aller R, Alarcón-Arís D, Miquel-Rio L, Ruiz-Bronchal E, Paz V, Campa L, Galofré M, Sgambato V, Bortolozzi A. Pavia-Collado R, et al. Among authors: miquel rio l. Int J Mol Sci. 2022 Feb 4;23(3):1807. doi: 10.3390/ijms23031807. Int J Mol Sci. 2022. PMID: 35163729 Free PMC article.
Human α-synuclein overexpression in mouse serotonin neurons triggers a depressive-like phenotype. Rescue by oligonucleotide therapy.
Miquel-Rio L, Alarcón-Arís D, Torres-López M, Cóppola-Segovia V, Pavia-Collado R, Paz V, Ruiz-Bronchal E, Campa L, Casal C, Montefeltro A, Vila M, Artigas F, Revilla R, Bortolozzi A. Miquel-Rio L, et al. Transl Psychiatry. 2022 Feb 24;12(1):79. doi: 10.1038/s41398-022-01842-z. Transl Psychiatry. 2022. PMID: 35210396 Free PMC article.
Food craving-like episodes during pregnancy are mediated by accumbal dopaminergic circuits.
Haddad-Tóvolli R, Ramírez S, Muñoz-Moreno E, Milà-Guasch M, Miquel-Rio L, Pozo M, Chivite I, Altirriba J, Obri A, Gómez-Valadés AG, Toledo M, Eyre E, Bortolozzi A, Valjent E, Soria G, Claret M. Haddad-Tóvolli R, et al. Among authors: miquel rio l. Nat Metab. 2022 Apr;4(4):424-434. doi: 10.1038/s42255-022-00557-1. Epub 2022 Apr 4. Nat Metab. 2022. PMID: 35379970 Free article.
Lipid nanoparticles for antisense oligonucleotide gene interference into brain border-associated macrophages.
Calero M, Moleiro LH, Sayd A, Dorca Y, Miquel-Rio L, Paz V, Robledo-Montaña J, Enciso E, Acción F, Herráez-Aguilar D, Hellweg T, Sánchez L, Bortolozzi A, Leza JC, García-Bueno B, Monroy F. Calero M, et al. Among authors: miquel rio l. Front Mol Biosci. 2022 Nov 3;9:887678. doi: 10.3389/fmolb.2022.887678. eCollection 2022. Front Mol Biosci. 2022. PMID: 36406277 Free PMC article.
Thalamic Foxp2 regulates output connectivity and sensory-motor impairments in a model of Huntington's Disease.
Rodríguez-Urgellés E, Casas-Torremocha D, Sancho-Balsells A, Ballasch I, García-García E, Miquel-Rio L, Manasanch A, Del Castillo I, Chen W, Pupak A, Brito V, Tornero D, Rodríguez MJ, Bortolozzi A, Sanchez-Vives MV, Giralt A, Alberch J. Rodríguez-Urgellés E, et al. Among authors: miquel rio l. Cell Mol Life Sci. 2023 Nov 21;80(12):367. doi: 10.1007/s00018-023-05015-z. Cell Mol Life Sci. 2023. PMID: 37987826 Free PMC article.
14 results