Miotto MC - Search Results

1

Heart failure-induced cognitive dysfunction is mediated by intracellular Ca²⁺ leak through ryanodine receptor type 2.

Dridi H, Liu Y, Reiken S, Liu X, Argyrousi EK, Yuan Q, Miotto MC, Sittenfeld L, Meddar A, Soni RK, Arancio O, Lacampagne A, Marks AR. Dridi H, et al. Among authors: miotto mc. Nat Neurosci. 2023 Aug;26(8):1365-1378. doi: 10.1038/s41593-023-01377-6. Epub 2023 Jul 10. Nat Neurosci. 2023. PMID: 37429912 Free PMC article.

2

Bioinorganic Chemistry of Parkinson's Disease: Affinity and Structural Features of Cu(I) Binding to the Full-Length β-Synuclein Protein.

Miotto MC, Pavese MD, Quintanar L, Zweckstetter M, Griesinger C, Fernández CO. Miotto MC, et al. Inorg Chem. 2017 Sep 5;56(17):10387-10395. doi: 10.1021/acs.inorgchem.7b01292. Epub 2017 Aug 18. Inorg Chem. 2017. PMID: 28820253

3

Phthalocyanines as Molecular Scaffolds to Block Disease-Associated Protein Aggregation.

Valiente-Gabioud AA, Miotto MC, Chesta ME, Lombardo V, Binolfi A, Fernández CO. Valiente-Gabioud AA, et al. Among authors: miotto mc. Acc Chem Res. 2016 May 17;49(5):801-8. doi: 10.1021/acs.accounts.5b00507. Epub 2016 May 2. Acc Chem Res. 2016. PMID: 27136297 Review.

4

A moderate metal-binding hydrazone meets the criteria for a bioinorganic approach towards Parkinson's disease: Therapeutic potential, blood-brain barrier crossing evaluation and preliminary toxicological studies.

Cukierman DS, Pinheiro AB, Castiñeiras-Filho SL, da Silva AS, Miotto MC, De Falco A, de P Ribeiro T, Maisonette S, da Cunha AL, Hauser-Davis RA, Landeira-Fernandez J, Aucélio RQ, Outeiro TF, Pereira MD, Fernández CO, Rey NA. Cukierman DS, et al. Among authors: miotto mc. J Inorg Biochem. 2017 May;170:160-168. doi: 10.1016/j.jinorgbio.2017.02.020. Epub 2017 Feb 22. J Inorg Biochem. 2017. PMID: 28249224

5

Copper binding to the N-terminally acetylated, naturally occurring form of alpha-synuclein induces local helical folding.

Miotto MC, Valiente-Gabioud AA, Rossetti G, Zweckstetter M, Carloni P, Selenko P, Griesinger C, Binolfi A, Fernández CO. Miotto MC, et al. J Am Chem Soc. 2015 May 27;137(20):6444-7. doi: 10.1021/jacs.5b01911. Epub 2015 May 15. J Am Chem Soc. 2015. PMID: 25939020

6

Spectroscopic and Theoretical Study of Cu(I) Binding to His111 in the Human Prion Protein Fragment 106-115.

Arcos-López T, Qayyum M, Rivillas-Acevedo L, Miotto MC, Grande-Aztatzi R, Fernández CO, Hedman B, Hodgson KO, Vela A, Solomon EI, Quintanar L. Arcos-López T, et al. Among authors: miotto mc. Inorg Chem. 2016 Mar 21;55(6):2909-22. doi: 10.1021/acs.inorgchem.5b02794. Epub 2016 Mar 1. Inorg Chem. 2016. PMID: 26930130 Free PMC article.

7

Bioinorganic chemistry of synucleinopathies: deciphering the binding features of Met motifs and His-50 in AS-Cu(I) interactions.

Miotto MC, Binolfi A, Zweckstetter M, Griesinger C, Fernández CO. Miotto MC, et al. J Inorg Biochem. 2014 Dec;141:208-211. doi: 10.1016/j.jinorgbio.2014.08.012. Epub 2014 Sep 3. J Inorg Biochem. 2014. PMID: 25218565

8

Site-specific copper-catalyzed oxidation of α-synuclein: tightening the link between metal binding and protein oxidative damage in Parkinson's disease.

Miotto MC, Rodriguez EE, Valiente-Gabioud AA, Torres-Monserrat V, Binolfi A, Quintanar L, Zweckstetter M, Griesinger C, Fernández CO. Miotto MC, et al. Inorg Chem. 2014 May 5;53(9):4350-8. doi: 10.1021/ic4031377. Epub 2014 Apr 11. Inorg Chem. 2014. PMID: 24725094

9

Disruption of zinc and copper interactions with Aβ(1-40) by a non-toxic, isoniazid-derived, hydrazone: a novel biometal homeostasis restoring agent in Alzheimer's disease therapy?

Hauser-Davis RA, de Freitas LV, Cukierman DS, Cruz WS, Miotto MC, Landeira-Fernandez J, Valiente-Gabioud AA, Fernández CO, Rey NA. Hauser-Davis RA, et al. Among authors: miotto mc. Metallomics. 2015 May;7(5):743-7. doi: 10.1039/c5mt00003c. Epub 2015 Apr 10. Metallomics. 2015. PMID: 25860559

10

Copper Coordination Features of Human Islet Amyloid Polypeptide: The Type 2 Diabetes Peptide.

Sánchez-López C, Cortés-Mejía R, Miotto MC, Binolfi A, Fernández CO, Del Campo JM, Quintanar L. Sánchez-López C, et al. Among authors: miotto mc. Inorg Chem. 2016 Oct 17;55(20):10727-10740. doi: 10.1021/acs.inorgchem.6b01963. Epub 2016 Oct 5. Inorg Chem. 2016. PMID: 27704849

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