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Page 1
Immunity against Moraxella catarrhalis requires guanylate-binding proteins and caspase-11-NLRP3 inflammasomes.
Enosi Tuipulotu D, Feng S, Pandey A, Zhao A, Ngo C, Mathur A, Lee J, Shen C, Fox D, Xue Y, Kay C, Kirkby M, Lo Pilato J, Kaakoush NO, Webb D, Rug M, Robertson AA, Tessema MB, Pang S, Degrandi D, Pfeffer K, Augustyniak D, Blumenthal A, Miosge LA, Brüstle A, Yamamoto M, Reading PC, Burgio G, Man SM. Enosi Tuipulotu D, et al. Among authors: miosge la. EMBO J. 2023 Mar 15;42(6):e112558. doi: 10.15252/embj.2022112558. Epub 2023 Feb 10. EMBO J. 2023. PMID: 36762431 Free PMC article.
Clostridium perfringens virulence factors are nonredundant activators of the NLRP3 inflammasome.
Mathur A, Kay C, Xue Y, Pandey A, Lee J, Jing W, Enosi Tuipulotu D, Lo Pilato J, Feng S, Ngo C, Zhao A, Shen C, Rug M, Miosge LA, Atmosukarto II, Price JD, Ali SA, Gardiner EE, Robertson AA, Awad MM, Lyras D, Kaakoush NO, Man SM. Mathur A, et al. Among authors: miosge la. EMBO Rep. 2023 Jun 5;24(6):e54600. doi: 10.15252/embr.202254600. Epub 2023 Apr 19. EMBO Rep. 2023. PMID: 37073791 Free PMC article.
Functional rare and low frequency variants in BLK and BANK1 contribute to human lupus.
Jiang SH, Athanasopoulos V, Ellyard JI, Chuah A, Cappello J, Cook A, Prabhu SB, Cardenas J, Gu J, Stanley M, Roco JA, Papa I, Yabas M, Walters GD, Burgio G, McKeon K, Byers JM, Burrin C, Enders A, Miosge LA, Canete PF, Jelusic M, Tasic V, Lungu AC, Alexander SI, Kitching AR, Fulcher DA, Shen N, Arsov T, Gatenby PA, Babon JJ, Mallon DF, de Lucas Collantes C, Stone EA, Wu P, Field MA, Andrews TD, Cho E, Pascual V, Cook MC, Vinuesa CG. Jiang SH, et al. Among authors: miosge la. Nat Commun. 2019 May 17;10(1):2201. doi: 10.1038/s41467-019-10242-9. Nat Commun. 2019. PMID: 31101814 Free PMC article.
TLR7 gain-of-function genetic variation causes human lupus.
Brown GJ, Cañete PF, Wang H, Medhavy A, Bones J, Roco JA, He Y, Qin Y, Cappello J, Ellyard JI, Bassett K, Shen Q, Burgio G, Zhang Y, Turnbull C, Meng X, Wu P, Cho E, Miosge LA, Andrews TD, Field MA, Tvorogov D, Lopez AF, Babon JJ, López CA, Gónzalez-Murillo Á, Garulo DC, Pascual V, Levy T, Mallack EJ, Calame DG, Lotze T, Lupski JR, Ding H, Ullah TR, Walters GD, Koina ME, Cook MC, Shen N, de Lucas Collantes C, Corry B, Gantier MP, Athanasopoulos V, Vinuesa CG. Brown GJ, et al. Among authors: miosge la. Nature. 2022 May;605(7909):349-356. doi: 10.1038/s41586-022-04642-z. Epub 2022 Apr 27. Nature. 2022. PMID: 35477763 Free PMC article.
DOCK2-deficiency causes defects in anti-viral T cell responses and poor control of herpes simplex virus infection.
Randall KL, Flesch IEA, Mei Y, Miosge LA, Aye R, Yu Z, Domaschenz H, Hollett NA, Russell TA, Stefanovic T, Wong YC, Goodnow CC, Bertram EM, Enders A, Tscharke DC. Randall KL, et al. Among authors: miosge la. bioRxiv [Preprint]. 2023 Aug 3:2023.08.02.551154. doi: 10.1101/2023.08.02.551154. bioRxiv. 2023. PMID: 37577614 Free PMC article. Updated. Preprint.
DOCK2-deficiency causes defects in anti-viral T cell responses and impaired control of herpes simplex virus infection.
Randall KL, Flesch IEA, Mei Y, Miosge LA, Aye R, Yu Z, Domaschenz H, Hollett NA, Russell TA, Stefanovic T, Wong YC, Seneviratne S, Ballard F, Hernandez Gallardo R, Croft SN, Goodnow CC, Bertram EM, Enders A, Tscharke DC. Randall KL, et al. Among authors: miosge la. J Infect Dis. 2024 Feb 15:jiae077. doi: 10.1093/infdis/jiae077. Online ahead of print. J Infect Dis. 2024. PMID: 38366567
A divergent transcriptional landscape underpins the development and functional branching of MAIT cells.
Koay HF, Su S, Amann-Zalcenstein D, Daley SR, Comerford I, Miosge L, Whyte CE, Konstantinov IE, d'Udekem Y, Baldwin T, Hickey PF, Berzins SP, Mak JYW, Sontani Y, Roots CM, Sidwell T, Kallies A, Chen Z, Nüssing S, Kedzierska K, Mackay LK, McColl SR, Deenick EK, Fairlie DP, McCluskey J, Goodnow CC, Ritchie ME, Belz GT, Naik SH, Pellicci DG, Godfrey DI. Koay HF, et al. Sci Immunol. 2019 Nov 22;4(41):eaay6039. doi: 10.1126/sciimmunol.aay6039. Sci Immunol. 2019. PMID: 31757835 Free PMC article.
SATB1 ensures appropriate transcriptional programs within naïve CD8+ T cells.
Nüssing S, Miosge LA, Lee K, Olshansky M, Barugahare A, Roots CM, Sontani Y, Day EB, Koutsakos M, Kedzierska K, Goodnow CC, Russ BE, Daley SR, Turner SJ. Nüssing S, et al. Among authors: miosge la. Immunol Cell Biol. 2022 Sep;100(8):636-652. doi: 10.1111/imcb.12566. Epub 2022 Jul 13. Immunol Cell Biol. 2022. PMID: 35713361 Free PMC article.
NINJ1 mediates plasma membrane rupture during lytic cell death.
Kayagaki N, Kornfeld OS, Lee BL, Stowe IB, O'Rourke K, Li Q, Sandoval W, Yan D, Kang J, Xu M, Zhang J, Lee WP, McKenzie BS, Ulas G, Payandeh J, Roose-Girma M, Modrusan Z, Reja R, Sagolla M, Webster JD, Cho V, Andrews TD, Morris LX, Miosge LA, Goodnow CC, Bertram EM, Dixit VM. Kayagaki N, et al. Among authors: miosge la. Nature. 2021 Mar;591(7848):131-136. doi: 10.1038/s41586-021-03218-7. Epub 2021 Jan 20. Nature. 2021. PMID: 33472215
34 results